调节性T细胞在慢性肝病中的变化 |
| |
引用本文: | 肖时湘,韩涛,王媛媛,朱争艳,阚志超.调节性T细胞在慢性肝病中的变化[J].陕西医学杂志,2010,39(7):831-833. |
| |
作者姓名: | 肖时湘 韩涛 王媛媛 朱争艳 阚志超 |
| |
作者单位: | 天津市第三中心医院消化科,天津,300170 |
| |
基金项目: | 天津市重点科技攻关专项资助项目,国家重点基础研究发展规划(973计划)资助项目 |
| |
摘 要: | 目的:观察调节性T细胞在慢性肝病中的变化及其临床意义。方法:用流式细胞仪检测患者的CD4+CD127loCD25hi-int调节性T细胞。比较不同慢性肝病患者(慢性乙型肝炎、乙肝肝硬化、肝癌)间CD4+CD127loCD25hi-int调节性T细胞的表达情况。结果:不同慢性肝病患者间调节性T细胞的表达有差异,但无统计学意义,肝癌患者最高,乙肝患者次之,肝硬化患者最低,但均高于健康对照。结论:调节性T细胞与慢性肝病显著相关。
|
关 键 词: | 肝疾病/免疫学 T淋巴细胞/免疫学 |
Relationship between regulatory thymus cell and chronic liver disease |
| |
Affiliation: | The Department of Gastroenterology,Tianjin Third Central Hospital(Tianjin 300170) Xiao Shixiang Han Tao Wang Yuanyuan et al |
| |
Abstract: | Objective:To investigate the change and the role of regulatory thymus cell in patient with chronic liver disease.Methods:CD4+CD127loCD25hi-int regulatory thymus cell (Treg) was tested by Flow Cytometry.The levels of Treg in patients with chronic liver disease (chronic hepatitis B,cirrhosis,liver cancer) were compared.Results:Treg level in patient with chronic liver disease group was significantly higher than healthy control group.But there wasn't significant differences among patients with chronic hepatitis B、cirrhosis and liver cancer.Conclusion:The levels of Treg is relation with chronic hepatic disease. |
| |
Keywords: | Liver dieases/immunology T-lymphocytes/immunology |
本文献已被 维普 万方数据 等数据库收录! |
|