体外受精-胚胎移植后宫内妊娠合并子宫肌壁间妊娠1例文献分析

目的探讨体外受精-胚胎移植(in vitro fertilization-embryo transfer,IVF-ET)术后发生宫内妊娠合并子宫肌壁间妊娠诊断、治疗及预防方法。方法回顾分析1例IVF-ET术后宫内妊娠合并子宫肌壁间妊娠诊疗经过并进行文献复习。结果患者冷冻移植2枚胚胎后妊娠,孕40 d,B超示宫内早孕合并右侧宫角肌层内妊娠,于西北妇女儿童医院行腹腔镜下子宫肌壁间妊娠清除术,术后宫内妊娠给予加强保胎治疗,现患者孕20周,宫内单胎妊娠。结论IVF-ET患者行多胚胎移植增加异位妊娠风险;IVF-ET术后宫内妊娠合并子宫肌壁间妊娠治疗方式应结合患者临床表现、辅助检查结果和患者自身意愿。

Intrauterine pregnancy with intramural pregnancy after in vitro fertilization-embryo transfer:a case report and literature review

Objective To investigate the diagnosis,treatment and prevention of intrauterine pregnancy with intramural pregnancy(IMP)after in vitro fertilization-embryo transfer(IVF-ET).Methods A retrospective clinical study and literature review were performed to analyze one intrauterine pregnancy with intramural pregnancy after IVF-ET.Results After double embryo transfer,the patient got conceived.Ultrasound showed early pregnancy in utero with intramural pregnancy on the 40th day of her pregnancy.So the patient underwent laparoscopic hysterectomy in Northwest Women's and Children's Hospital.The patient is now 20 weeks pregnant,and has a intrauterine singleton pregnancy.Conclusion IVF-ET increases the risk of ectopic pregnancy.The treatment of intrauterine pregnancy with intramural pregnancy should take clinical manifestations,examination results and the patient's own wishes into account.