高压氧辅助治疗对急性脑梗死伴认知功能障碍患者认知功能及神经功能恢复情况的影响分析

目的探讨对急性脑梗死伴认知功能障碍患者采用高压氧辅助治疗对认知功能及神经功能恢复情况的影响。方法42例急性脑梗死伴认知功能障碍患者,根据治疗方法不同分为实验组及对照组,每组21例。对照组仅给予常规急性脑梗死药物治疗,实验组在常规急性脑梗死药物治疗基础上给予高压氧治疗。比较两组患者入院当天、治疗第30天简易精神状态检查量表(MMSE)评分及入院当天、治疗第3天、第30天美国国立卫生研究院卒中量表(NIHSS)评分。结果入院当天,两组患者MMSE评分比较差异无统计学意义(P>0.05);治疗第30天,实验组患者MMSE评分为(24.2±3.5)分,高于对照组的(21.3±2.6)分,差异具有统计学意义(P<0.05)。入院当天、治疗第3天,两组患者NIHSS评分比较差异无统计学意义(P>0.05);治疗第30天,实验组患者NIHSS评分为(12.2±1.7)分,明显低于对照组的(14.3±2.4)分,差异具有统计学意义(P<0.05)。结论高压氧辅助治疗对急性脑梗死患者认知功能及神经功能的恢复可能有促进作用。

Effect of hyperbaric oxygen adjuvant therapy on the recovery of cognitive function and neurological function in patients with acute cerebral infarction and cognitive impairment

Objective To discuss the effect of hyperbaric oxygen adjuvant therapy on the recovery of cognitive function and neurological function in patients with acute cerebral infarction and cognitive impairment.Methods A total of 42 patients with acute cerebral infarction and cognitive impairment were divided into experimental group and control group according to different treatment methods,with 21 cases in each group.The control group was treated with conventional drug treatment for acute cerebral infarction,while the experimental group was treated with hyperbaric oxygen therapy on the basis of conventional drug treatment for acute cerebral infarction.The mini mental state examination(MMSE)score on the day of admission and the 30th day of treatment,and NIHSS scores on the day of admission,on the 3rd and 30th day of treatment were compared between the two groups.Results On the day of admission,there was no statistically significant difference in MMSE score between the two groups(P>0.05).On the 30th day of treatment,MMSE score(24.2±3.5)points of the experimental group was higher than(21.3±2.6)points of the control group,and the difference was statistically significant(P<0.05).On the day of admission and 3rd day of treatment,there was no statistically significant difference in National Institutes of Health stroke scale(NIHSS)score between the two groups(P>0.05).On the 30th day of treatment,NIHSS score(12.2±1.7)points of the experimental group was obviously lower than(14.3±2.4)points of the control group,and the difference was statistically significant(P<0.05).Conclusion Hyperbaric oxygen therapy may promote the recovery of cognitive function and nerve function in patients with acute cerebral infarction.