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烧伤后血清对T淋巴细胞抑制的实验研究
引用本文:梁华平,赵鄞生.烧伤后血清对T淋巴细胞抑制的实验研究[J].解放军医学杂志,1991,16(6):446-448.
作者姓名:梁华平  赵鄞生
作者单位:第三军医大学野战外科研究所 (梁华平),第三军医大学野战外科研究所(赵鄞生)
摘    要:

关 键 词:烧伤  淋巴细胞  白细胞介素

A STUDY ON SUPPRESSIVE ACTIVITY OF POSTBURN SERUM ON T LYMPHOCYTE PROLIFERATION RESPONSE
Liang Huaping,Zhao Yinsheng.A STUDY ON SUPPRESSIVE ACTIVITY OF POSTBURN SERUM ON T LYMPHOCYTE PROLIFERATION RESPONSE[J].Medical Journal of Chinese People's Liberation Army,1991,16(6):446-448.
Authors:Liang Huaping  Zhao Yinsheng
Affiliation:Liang Huaping,Zhao Yinsheng. Institute of Surgical Research,Third Military Medical College,Chongqing
Abstract:The effect of postburn serum on T lymphocyte proliferation response was studied. The results showed that postburn serum was able to inhibit T lymphocyte transformation. The degree of serum suppression correlated with reduced T lymphocyte transformation after burn. Postburn serum also showed significant suppressive activities upon both interleukin 2 (IL-2) production and interaction betweeen IL-2 and IL-2 receptor (IL-2R), but had no significant effect on interleukin 1 (1L-1) producticn. This result indicated that postburn serum might inhibit IL-2 production and response through certain pathway other than IL-1 production, resulting in impaired T lymphocyte proliferation response.
Keywords:Burn Lymphocyte Interleukin 1 Interleukin 2
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