冠状动脉疾病报告与数据系统在冠心病患者危险因素分析中的应用

目的：探讨冠状动脉疾病报告与数据系统（CAD-RADS）在冠状动脉粥样硬化性心脏病（冠心病）诊断中的应用及其危险因素，阐明危险因素对CAD-RADS诊断冠心病的影响强度。方法：收集266例临床怀疑冠心病患者的冠状动脉CT血管造影（CTA）影像资料和临床相关资料，采用CAD-RADS分级法将患者分为冠心病组（n=174）和非冠心病组（n=69）。分析2组患者年龄、性别、高血压、高血脂、糖尿病、吸烟、尿酸（UA）水平和血浆纤维蛋白原（FIB）水平；采用单因素和多因素Logistic回归分析方法分析CAD-RADS系统诊断冠心病的相关危险因素。结果：与非冠心病组比较，冠心病组患者中男性、高血压、糖尿病和吸烟者所占比例明显升高（P<0.05），冠心病组患者平均年龄大、UA水平高（P<0.05）。多因素Logistic回归分析，年龄和糖尿病是冠状动脉CAD-RADS诊断冠心病的最显著危险因素。结论：CAD-RADS诊断冠心病受到多种危险因素的影响，其中年龄和糖尿病是最显著的独立相关危险因素。

Application of Coronary Artery Disease-Reporting and Data System in risk factor analysis of patients with coronary artery disease

Objective:To investigate the application of Coronary Artery Disease-Reporting and Data System (CAD-RADS) in the diagnosis of coronary atherosclerotic heart disease(CAD) and its risk factors,and to clarify the effective strength of different risk factors in the diagnosis of CAD by using CAD-RADS.Methods:All the data of 266 patients,who were initially suspected with CAD and underwent CT angiography,were collected and diagnosed by using CAD-RADS and were divided into CAD group(n=174) and non-CAD group(n=69).The informations of age,gender,hypertension,hyperlipemia,diabetes,smoking,serum uric acid (UA) levels,and plasma fibrinogen (FIB) levels of the patients in two groups were analyzed;single factor analysis and multivariate Logstic regression analysis were used to analyze the risk factors of CAD diagnosed by CAD-RADS.Results:Compared with non-CAD group,the ratios of male,hypertension,diabetes,smoking of the patients in CAD group were increased (P<0.05),and the age and the level of UA of the patients in CAD group were also increased (P<0.05).The Logistic regression analysis results showed that age and diabetes were the independent risk factors for CAD diagnosed by CAD-RADS.Conclusion:There are many independent risk factors for CAD diagnosed by CAD-RADS,and age and diabetes are the most correlated risk factors for CAD.