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湖北恩施地区流感局部暴发流行病原学分析
引用本文:冯玲玲 霍细香 叶国军 肖红雨 杨继先 陈朴 龚镇奎. 湖北恩施地区流感局部暴发流行病原学分析[J]. 公共卫生与预防医学, 2004, 15(3): 13-15
作者姓名:冯玲玲 霍细香 叶国军 肖红雨 杨继先 陈朴 龚镇奎
作者单位:[1]湖北省疾病预防控制中心传染病防治研究所,武汉430079 [2]宣恩县疾病预防控制中心 [3]恩施自治州疾病预防控制中心
摘    要:目的对恩施地区2003年3月上、中旬发生的两起流感局部暴发流行进行病原学分析。方法采集患者咽拭子进行病毒分离鉴定,采集急性期和恢复期双份血进行抗流感病毒IgG抗体测定。结果证实湖北恩施地区出现的流感局部暴发流行是由B型流感病毒引起的,分离的B型流感病毒的抗原性与2001年香港分离株(B/香港/维多利亚30/2001)和浙江分离株(B/浙江/2/2001)很接近,而与1999年四川分离株(B/四川/397/1999)和2001年上海分离株(B/上海/20/2001)相差甚远。结论湖北省恩施地区2003年3月流感局部暴发流行是由流感病毒B型引起的。

关 键 词:流行性感冒 病毒分离 血凝抑制试验
文章编号:1006-2483(2004)03-0013-03

The Pathological Analysis on an Outbreak of Influenza in Enshi Prefecture,Hubei Province
FENG Ling-ling,HUO Xi-xiang,YE Guo-jun,XIAO Hong-yu,YANG Ji-xian,CHEN Pu,GONG Zhen-kui Institute of infection diseases research and control,Hubei Center of diseases prevention and Control,Wuhan ,China. The Pathological Analysis on an Outbreak of Influenza in Enshi Prefecture,Hubei Province[J]. Journal of Public Health and Preventive Medicine, 2004, 15(3): 13-15
Authors:FENG Ling-ling  HUO Xi-xiang  YE Guo-jun  XIAO Hong-yu  YANG Ji-xian  CHEN Pu  GONG Zhen-kui Institute of infection diseases research  control  Hubei Center of diseases prevention  Control  Wuhan   China
Affiliation:FENG Ling-ling,HUO Xi-xiang,YE Guo-jun,XIAO Hong-yu,YANG Ji-xian,CHEN Pu,GONG Zhen-kui Institute of infection diseases research and control,Hubei Center of diseases prevention and Control,Wuhan 430079,China
Abstract:Objective Pathogenic analysis of 2 influenza outbreaks were carried out in En-shi prefecture by March,2003. The isolated and antigenic characteristics were analyzed from the prevalence of influenza in the school of Enshi.Methods Chicken embryo inoculation was used to isolate virus from patient's swab sample, IgG antibody was detected, using acute and convedecent-phase serum pair.Results Two field strains were obtained from 10 patient swabs , influenza B was identificated, its antigenicity was similar to B/Hong Kong/Victoria/2001 and B/Zhejiang2/2001,while quite different with B/Sichuan/397/1999 and B/Shanghai/20/2001.Conclusion The pathogen of the outbreak in Enshi was the influenza B virus.
Keywords:Influenza  Viruses isolation  Hemagglutinative inhibitory test
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