温阳活血方联合常规心脏康复改善冠心病经皮冠状动脉介入术后患者生活质量的临床研究

目的:探讨温阳活血方联合常规心脏康复对冠心病经皮冠状动脉介入术后患者生活质量的改善效果,为中西医结合心脏康复提供临床新证据和新思路.方法:选取2017年6月至2019年11月上海中医药大学附属市中医医院、同济大学附属上海市第十人民医院行经皮冠状动脉介入术成功4周后的患者60例,按随机、对照原则分为治疗组30例和对照组3...

Clinical Study of Wenyang Huoxue Decoction Combined with Routine Cardiac Rehabilitation on Improvement of Life Quality of Patients with Coronary Heart Disease After Intervention

OBJECTIVE:To probe into the clinical study of Wenyang Huoxue decoction combined with routine cardiac rehabilitation on improvement of life quality of patients with coronary heart disease after intervention,so as to provide new clinical evidence and new ideas for the cardiac rehabilitation with the combination of traditional Chinese medicine and Western medicine.METHODS:From Jun.2017 to Nov.2019,60 patients undergoing successful percutaneous coronary intervention in Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine and Tenth People’s Hospital of Tongji University were extracted to be divided into the treatment group and the control group according to the principle of randomization and comparison,with30 cases in each group.Patients in both groups were treated with routine western medicine and cardiac rehabilitation.The treatment group was given Wenyang Huoxue decoction in the morning and evening,for 12 weeks as a course of treatment.Traditional Chinese medicine syndrome scores,Seattle angina questionnaire(SAQ)score and the Medical Outcomes Study item short from health survey(SF-36)of two groups were observed before and after treatment.RESULTS:After treatment,the traditional Chinese medicine syndrome score in both groups was improved significantly compared with that before treatment,and the improvement in the treatment group was better than that in the control group,with statistically significant differences(P<0.05).The total effective rate in the treatment group was 90.0%(27/30),significantly higher than 66.7%(20/30)in the control group,the difference was statistically significant(P<0.05).After treatment,the SAQ scores(including physical activity limitation,angina stability,angina pectoris frequency,treatment satisfaction and disease cognition)of the treatment group were significantly better than those of the control group,and the differences were statistically significant(P<0.05);the SF-36 scores in the treatment group after treatment were significantly higher than those before treatment;the scores of physiology,physiological function,physical pain and energy in the control group were significantly higher than those before treatment;after treatment,the scores of physical pain,mental health,social function,emotional function and overall health in the treatment group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).CONCLUSIONS:Wenyang Huoxue decoction combined with routine cardiac rehabilitation can improve the traditional Chinese medicine syndrome score,angina pectoris and life quality.