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反相高效液相色谱法测定苯扎贝特的含量
引用本文:吴洁.反相高效液相色谱法测定苯扎贝特的含量[J].化学试剂,2004,26(5):285-286.
作者姓名:吴洁
作者单位:淮阴工学院,生化系,江苏,淮安,223001
摘    要:研究了采用反相高效液相色谱测定苯扎贝特含量的方法 ,以磷酸盐缓冲液 (0 0 1mol/L的磷酸二氢钾用磷酸调节pH至 3 8) 甲醇 (4∶6 )为流动相 ,采用HypersilC18柱 (5 μm ,4 6mm× 15 0mm) ,检测波长为 2 30nm ,苯扎贝特在 0 0 114~0 114mg/mL范围内线性相关 ,回归方程为 :A =1 0 5× 10 4c(mg/mL) +2 70× 10 2 ,r =0 9997,此法简便、快速、结果准确可靠

关 键 词:反相高效液相色谱法  苯扎贝特
文章编号:0258-3283(2004)05-0285-02

Determination of benzafibrate by reversed-phase high performance liquid chromatography
WU Jie.Determination of benzafibrate by reversed-phase high performance liquid chromatography[J].Chemical Reagents,2004,26(5):285-286.
Authors:WU Jie
Abstract:A HPLC method was established for the determination of benzafibrate.Hypersil C_(18) was used as the stationary phase and 0.01 mol/L KH_2PO_4-CH_3OH as the mobile phase.The method was simple,rapid and reliable.It was applied not only in determination of its content,but also in determination of the related substances.
Keywords:HPLC  benzafibrate
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