| 125^I粒子植入联合动脉灌注化疗治疗不可切除性肺癌 |
| |
| 引用本文： | 刘瑞宝,杨光,崔亚利,刘岩,潘雪玲,何东风,马建群,隋林.125^I粒子植入联合动脉灌注化疗治疗不可切除性肺癌[J].介入放射学杂志,2009,18(6):453-456. |
| |
| 作者姓名： | 刘瑞宝 杨光 崔亚利 刘岩 潘雪玲 何东风 马建群 隋林 |
| |
| 作者单位： | 哈尔滨医科大学附属肿瘤医院介入科,150081 |
| |
| 摘 要： | 目的 探讨CT引导下125I粒子植入联合动脉灌注化疗治疗不可切除肺癌的价值.方法 30例不可切除性肺癌患者随机分为两组.A组14例,125I粒子植入术前或后1周内行动脉灌注化疗;B组16例,单纯125I粒子植入治疗.两组患者125I粒子植入2个月后行胸部CT检查,按RECIST标准判定疗效并进行生存分析.结果 30例患者全部按计划完成治疗.A组植入粒子552枚,9例行了2次动脉灌注化疗;B组共植入125I粒子603枚.CT复查显示:A组完全缓解(CR)0例,部分缓解(PR)10例,稳定(SD)4例,进展(PD)0例,治疗有效率为71.4%;B组完全缓解(CR)0例,部分缓解(PR)10例,稳定(SD)5例,进展(PD)1例,治疗有效率为62.5%.两组治疗有效率差异无统计学意义(P＞0.05).1年生存率分别为78.6%和 62.5%,生存期差异有统计学意义(P＜0.05).结论 125I粒子植入联合动脉灌注化疗是治疗不可切除性肺癌的一种有效方法,可显著延长患者的生存期.
|
| 关 键 词： | 肺癌 125I粒子 组织问插植 动脉灌注化疗 介人 |
Evaluation of ~(125)I seed implantation combined with arterial infusion chemotherapy in treating unresectable lung cancer |
| |
| LIU Rui-bao,YANG Guang,CUI Ya-li,LIU Yan,PAN Xue-ling,HE Dong-feng,MA Jian-qun,SUI Lin.Evaluation of ~(125)I seed implantation combined with arterial infusion chemotherapy in treating unresectable lung cancer[J].Journal of Interventional Radiology,2009,18(6):453-456. |
| |
| Authors: | LIU Rui-bao YANG Guang CUI Ya-li LIU Yan PAN Xue-ling HE Dong-feng MA Jian-qun SUI Lin |
| |
| Affiliation: | LIU Rui-bao,YANG Guang,CUI Ya-li,LIU Yan,PAN Xue-ling,HE Dong-feng,MA Jian-qun,SUI Lin. Department of Interventional Radiology,Tumor Hospital,Harbin Medical University,Harbin 150081,China |
| |
| Abstract: | Objective To assess the therapeutic effect of CT-guided 125I seed implantation combined with arterial infusion chemotherapy in treating unresectable lung cancer. Methods Thirty patients with unresectable non-small call lung cancer were randomly divided into two groups. Group A (study group,n = 14)was receiving arterial infusion chemotherapy one week before and one week after 125I seed implantation. Group B (control group,n = 16) was receiving 125I seed implantation only. Two months after 125I seed implantat... |
| |
| Keywords: | lung cancer 125I seed brachytherapy arterial infusion chemotherapy interventional |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
