麻痹性痴呆14例临床特征

目的探讨麻痹性痴呆(GPI)的临床类型、临床表现。方法分析14例麻痹性痴呆患者的临床资料。结果 14例麻痹性痴呆主要表现为精神症状和神经系统症状,门诊与入院诊断的误诊率高达100%,住院后均经实验室检查梅毒螺旋体凝集试验(TPPA)阳性而确诊。结论麻痹性痴呆易被误诊,诊断依据临床流行病学资料、临床表现、血清和脑脊液梅毒抗体检测阳性可确诊。作为一种可治性痴呆,早期的预防和观察识别有着非常重要的意义。

The clinical symptoms of fourteen cases patients with of general paresis of insane

Objective To investigate the clinical type,clinical symptoms points of general paresis of insane.Methods We collected the clinical data of fourteen cases of patients with general paresis of insane in Nanjing brain hospital from January 2001 to December 2009.Results These patients were mainly for the psychiatric symptoms and neurological symptoms,so there was 100% misdiagnosis rate in out-patient diagnosis and admission diagnosis,All patients were confirmed that they were infected syphilis by serum and TPPA tests in hospital.Conclusion General paresis of insane diagnosis to cause high rate of missed diagnosis.Epidemiologic data medical history and clinical provide import evidence for diagnosis.Confirmed can be made to blood serum tests and cerebrospinal fluid syphilis antibody tests.Early diagnosis is very important for syphilis that may be cured.The careful observation and identification of clinical symptoms by doctors are very important.