甘肃省1304例甲状腺手术围手术期抗菌药物应用调查

目的了解某省各级医疗机构甲状腺手术围手术期抗菌药物预防使用情况。方法对2011年1月1日—2013年12月31日该省各类甲状腺手术进行目标性监测,并对调查结果进行分析。结果共调查1 304例甲状腺手术,1 294例(99.23%)为择期手术;手术持续时间≤2 h者1 051例,占80.60%;抗菌药物使用率为96.70%;术前30 min给药者196例,占15.54%;抗菌药物使用时间48 h者887例,占70.34%;使用第一代头孢、克林霉素的占19.53%。结论该省甲状腺手术中存在抗菌药物选择不当、用药时机不当、用药时间过长、无指征用药现象等问题,应加大抗菌药物管理力度,促进抗菌药物合理使用。

Investigation on perioperative antimicrobial prophylaxis in 1 304 cases of thyroid operation in Gansu Province

ObjectiveTo investigate perioperative antimicrobial prophylaxis in thyroid operation at all levels of hospitals in a province.MethodsFrom January 1,2011 to December 31,2013, all kinds of thyroid operation in a province were conducted targeted monitor, investigated results were analyzed.ResultsA total of 1 304 cases of thyroid operation were investigated, 1 294 (99.23%) were elective operation; duration of operation of 1 051 cases (80.60%) were ≤2 hours; antimicrobial use rate was 96.70%; 196 patients (15.45%) were administered 30 minutes before operation, 887 patients (70.34%) used antimicrobial agents for >48 hours; 19.53% of patients used the first generation cephalosporins and clindamycin.ConclusionThere are some problems in antimicrobial use in thyroid operation in this province, such as inappropriate choice of antimicrobial agents, improper administration time， long time use of antimicrobial agents， and use antimicrobial agents without indications. Management of antimicrobial agents should be strengthened, so as to promote the rational use of antimicrobial agents.