| 一级直链溴化物的一锅法羟醛缩合反应 |
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| 引用本文： | 邵春雁,邱太源,孙小强. 一级直链溴化物的一锅法羟醛缩合反应[J]. 化学试剂, 2011, 33(2): 187-189 |
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| 作者姓名： | 邵春雁 邱太源 孙小强 |
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| 作者单位： | 1. 江苏工业学院,化学化工学院,江苏,常州,213164
2. 常州元朔化工科技有限公司,江苏,常州,213164 |
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| 基金项目： | 常州市科技型中小企业技术创新资金计划资助项目 |
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| 摘 要： | 研究了3个一级直链溴化物的一锅法羟醛缩合反应.分别以1-溴己烷、1-溴庚烷、1-溴辛烷为原料,用吡啶氮氧化物氧化,无水碳酸钠作为碱,甲苯作为溶剂,一锅法反应得到羟醛缩合反应产物,产率48.0%～54.9%.产品结构经1HNMR、MS、IR进行表征.
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| 关 键 词： | 溴化物 一锅法 羟醛缩合 |
One-pot aldol condensation of primary straight-chain bromides |
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| SHAO Chun-yan,QUI Tai-yuan,SUN Xiao-qiang. One-pot aldol condensation of primary straight-chain bromides[J]. Chemical Reagents, 2011, 33(2): 187-189 |
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| Authors: | SHAO Chun-yan QUI Tai-yuan SUN Xiao-qiang |
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| Affiliation: | SHAO Chun-yan1,QIU Tai-yuan*2,SUN Xiao-qiang1 (1.School of Chemistry and Chemical Engineering,Jiangsu Polytechnic University,Changzhou 213164,China,2.Changzhou Yuanshuo Chemical Techonologies Co.,Ltd.,China) |
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| Abstract: | This article investigated one-pot aldol condensation reactions involving primary straight-chain bromoalkanes.Three products were synthesized using 1-bromohexane,1-bromoheptane and 1-bromoctane as starting materials,pyridine-N-oxide as the oxidizer,sodium carbonate as the base,and toluene as the solvent.The foregoing one-pot synthesis reactions gave product yields in the range of 48.0% to 54.9%.The structures of the synthesized aldols were verified by 1HNMR,MS and IR spectroscopy. |
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| Keywords: | bromoalkanes one-pot synthesis aldol condensation |
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