血高催乳素血症导致男性性功能障碍的诊治分析

目的：分析血高催乳素血症导致的男性性功能障碍的诊断与治疗策略。方法：回顾性分析我院男科2011年至2012年收治的32名血高催乳素血症导致的男性性功能障碍患者的诊疗资料，总结血高催乳素血症导致男性性功能障碍的诊断与治疗方法。所有数据均建立Excel2013数据库，并采取SPSS19．0的统计学软件进行数据分析，计量资料均采取t检验，分析治疗前后患者血清性激素的变化。结果：32例患者中有特发性高催乳素血症23例（71．88％）、有垂体腺瘤4例（12．50％）、有微腺瘤5例（15．63％）。有勃起功能障碍29例（90．63％）、有性欲减退32例（100．00％）、有性高潮障碍7例（21．88％）。32例患者治疗后的血清催乳素含量明显低于治疗前，差异具有统计学意义（P〈0．01）。32例患者治疗后的黄体生成素、卵泡刺激素以及睾酮水平均要明显高于治疗前，差异具有统计学意义（P〈0．01）。经治疗后32例患者的勃起功能障碍、性欲减退以及高潮障碍等症状均有所改善。结论：高催乳素血症导致的男性性功能障碍经过病史采集、临床特征、勃起功能指数测定、体格检查、激素测定以及垂体的影像学检查可明确诊断，甲磺酸溴隐亭与十一酸睾酮的治疗效果较好，值得临床推广。

Diagnosis and treatment of male sexual dysfunction caused by hyperprolaetinemia

Objectives： To analyze the diagnostic and therapeutic strategies of male sexual dysfunction caused by hyperprolactinemia. Methods ： A retrospective analysis of the data of 32 male subjects with sexual dys- function caused by hyperprolactinemia treated in our hospital from 2011 to 2012 was conducted to summarize the di- agnostic and therapeutic methods of male sexual dysfunction caused by hyperprolactinemia. All data were put into Excel 2013 database and statistical software SPSS19.0 was used for data analysis; measurement data were taken t test to analyze the changes of serum sex hormones before and after treatment. Results： 1 ） There were 23 cases （71.88%） of idiopathic hyperprolactinemia, 4 cases （ 12.50% ） of micro adenoma and 5 cases （ 15.63% ） of pitu- itary adenoma among the 32 patients. There were 29 cases （90. 63% ） of erectile dysfunction, 32 cases （ 100. 00% ） of decreased libido and 7 cases （21.88%） of orgasmic disorder among the 32 patients. 2） The serum prolactin levels of 32 patients after treatment were significantly lower than that before the treatment, with statistically significant difference （P 〈 0.01 ） ; The levels of luteinizing hormone, follicle -stimulating hormone and testosterone of 32 patients after treatment were significantly higher than those before the treatment, with statistically significant difference （P 〈 0.01 ）. 3） After treatment, the erectile dysfunction, decreased libido, orgasmic dysfunction and other symptoms of 32 patients were improved. Conclusion： Male sexual dysfunction caused by hyperprolactinemia can be confirmed through history taking, clinical characteristics, erectile function index determination, physical ex- amination, hormonal measurement and imaging of pituitary. The effcacy of Bromocriptine Mesylate and testosterone undecanoate is better and worthy of promotion.