Solubility of hinokitiol in supercritical fluids; measurement and correlation

Supercritical fluid technology has been an alternative for purification and separation of biological compounds in cosmetic, food, and pharmaceutical products. Solubility information of biological compounds in supercritical fluids is essential for choosing a supercritical fluid processes. The equilibrium solubility of hinokitiol was measured in supercritical carbon dioxide and ethane with a static method in the pressure range from 8 to 40MPa and at temperatures equal to 313.2, 323.2 and 333.2 K. The experimental data were correlated well by Peng-Robinson equation of state and quasi-chemical nonrandom lattice fluid model.