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棉团铁线莲化学成分研究Ⅰ
引用本文:董彩霞,史社坡,武可泗,屠鹏飞.棉团铁线莲化学成分研究Ⅰ[J].中国中药杂志,2006,31(20):1696-1699.
作者姓名:董彩霞  史社坡  武可泗  屠鹏飞
作者单位:1. 北京大学,药学院,北京,100083;河北以岭医药研究院,河北,石家庄,050035
2. 北京大学,药学院,北京,100083
3. 河北以岭医药研究院,河北,石家庄,050035
摘    要:目的:研究棉团铁线莲Clematis hexapetala的干燥根及根茎的化学成分。方法:利用溶剂提取,硅胶柱色谱和高效液相色谱等手段进行分离、纯化,根据理化性质和波谱数据进行结构鉴定。结果:分离鉴定了9个化合物,分别为:木栓酮(1),白头翁素(2),β-谷甾醇(3),棕榈酸(4),香草酸(5),异落叶松脂素(6),5-羟甲基-2-呋喃酮(7),正壬烷(8),胡萝卜苷(9)。结论:均为首次从该植物中分离得到。

关 键 词:棉团铁线莲  化学成分  结构鉴定
文章编号:1001-5302(2006)20-1696-04
收稿时间:2005-12-13
修稿时间:2005-12-13

Studies on chemical constituents from root of Clematis hexapetala
DONG Cai-xia ; SHI She-po ;WU Ke-si ;TU Peng-fei.Studies on chemical constituents from root of Clematis hexapetala[J].China Journal of Chinese Materia Medica,2006,31(20):1696-1699.
Authors:DONG Cai-xia ; SHI She-po ;WU Ke-si ;TU Peng-fei
Affiliation:1. School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100083, China ; 2. Hebei Yiling Medicinal Institute, Shijiazhuang, 050035, China
Abstract:OBJECTIVE: To study the chemical constituents from the roots and rhizomes of Clematis hexapetala. METHOD: The compounds were separated by means of solvent extraction, repeated chromatography with silica gel and HPLC. The structures were determined by spectral analysis. RESULT: Nine compounds were isolated as friedelin (1) , anemonin (2) , beta-sitosterol (3) , palmitic acid (4) , vanillic acid (5) , isolariciresinol (6) , 5-hydroxumethyl-5H-furan-2-one (7) , n-nonane (8) , daucosterol (9). CONCLUSION: All the compounds were isolated from the plant for the first time.
Keywords:Clematis hexapetala  chemical constituents  structure determination
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