| β3-肾上腺素受体激动剂类减肥药的研究进展 |
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| 引用本文： | 尹健,陈再新,张奕华. β3-肾上腺素受体激动剂类减肥药的研究进展[J]. 中国医药工业杂志, 2005, 36(3): 180-184 |
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| 作者姓名： | 尹健 陈再新 张奕华 |
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| 作者单位： | 1. 中国药科大学新药研究中心,江苏,南京,210009
2. 江苏亚邦药物研发有限公司,江苏,南京,210024 |
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| 摘 要： | β3-肾上腺素受体可调节人体热量平衡、葡萄糖代谢、能量消耗并纠正产热不足,可用于治疗肥胖症和2型糖尿病.选择性β3-肾上腺素受体激动剂主要有芳基乙醇胺和芳氧基丙醇胺两类,本文对这些化合物的研究进展进行了综述.
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| 关 键 词： | β3-肾上腺素受体 激动剂 减肥药 综述 |
| 文章编号： | 1001-8255(2005)03-0180-05 |
Progress of Research and Development of β3-Adrenoceptor Agonists as Antiobesity Drugs |
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| YIN Jian,CHEN Zai-Xin,ZHANG Yi-Hua. Progress of Research and Development of β3-Adrenoceptor Agonists as Antiobesity Drugs[J]. , 2005, 36(3): 180-184 |
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| Authors: | YIN Jian CHEN Zai-Xin ZHANG Yi-Hua |
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| Abstract: | The b3-adrenoceptor plays a role in energy balance and glucose homeostasis. b3-Adrenoceptor agonisthas promising potential to be a therapeutic agent in the treatment of obesity and type 2 diabetes. Selective b3-adrenoceptoragonists fall into two main chemical classes, arylethanolamines and aryloxypropanolamines. This review is focused on theprogress of research and development of these compounds as antiobesity drugs. |
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