| 非酒精性脂肪性肝病患者血清补体C3水平的检测及意义 |
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| 引用本文： | 蒋晓颖.非酒精性脂肪性肝病患者血清补体C3水平的检测及意义[J].中国卫生检验杂志,2019(15):1870-1873. |
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| 作者姓名： | 蒋晓颖 |
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| 作者单位： | 湖州市第一人民医院检验科 |
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| 摘 要： | 目的本研究通过检测血清补体C3水平进一步探索非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)发生发展的深层机制。方法测定187例经腹部超声确诊的NAFLD患者和171例健康对照者血清补体C3水平及其他生化标志物和体质量等人体参数学指标。结果与对照组比较,NAFLD组血清补体C3水平明显升高(P <0. 001);NAFLD研究对象中ALT异常组(ALT≥40 U/L)血清补体C3水平显著高于ALT正常组(ALT <40 U/L);逻辑回归分析显示血清补体C3水平升高是预测NAFLD发生以及进展期肝纤维化的独立危险因素(P <0. 05)。结论血清补体C3在NAFLD发生发展中起着重要作用。
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| 关 键 词： | 非酒精性脂肪性肝病 进展性纤维化 补体系统 |
Detection and significance of serum complement C3 level in patients with nonalcoholic fatty liver disease |
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| JIANG Xiao-ying.Detection and significance of serum complement C3 level in patients with nonalcoholic fatty liver disease[J].Chinses Journal of Health Laboratory Technology,2019(15):1870-1873. |
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| Authors: | JIANG Xiao-ying |
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| Affiliation: | (Clinical Laboratory, the First People's Hospital of Huzhou, Hiizhou, Zhejiang 313000, China) |
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| Abstract: | JIANG Xiao-ying(Clinical Laboratory, the First People's Hospital of Huzhou, Hiizhou, Zhejiang 313000, China) |
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| Keywords: | Nonalcoholic fatty liver disease Advanced fibrosis Complement system |
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