| 正交试验法优选痛利舒颗粒水提工艺 |
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| 引用本文： | 杨龙飞,丁晓彦,高燕,国锦,孙启慧,赵渤年. 正交试验法优选痛利舒颗粒水提工艺[J]. 山东科学, 2018, 31(1): 23-29. DOI: 10.3976/j.issn.1002-4026.2018.01.004 |
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| 作者姓名： | 杨龙飞 丁晓彦 高燕 国锦 孙启慧 赵渤年 |
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| 作者单位： | 1.山东中医药大学,山东 济南 250355;2.山东省中医药研究院,山东省中药质量标准研究重点实验室,山东 济南 250014 |
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| 基金项目： | 山东省中医药科技发展计划（2015-171） |
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| 摘 要： | 采用正交试验法,以栀子苷含量、芍药苷含量、得膏率为评价指标,优选痛利舒颗粒的水提工艺参数。实验结果表明,最佳水提工艺参数为8倍量水,煎煮3次,每次2 h。该研究优选的工艺合理可行,提取效率高,可做为痛利舒颗粒的水提工艺,适用于工业生产。
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| 关 键 词： | 痛利舒颗粒 水提工艺 含量测定 得膏率 正交试验 |
| 收稿时间： | 2017-10-11 |
Optimization of water extraction process for Tonglishu Granuleby orthogonal experiment |
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| YANG Long-fei,DING Xiao-yan,GAO Yan,GUO Jin,SUN Qi-hui,ZHAO Bo-nian. Optimization of water extraction process for Tonglishu Granuleby orthogonal experiment[J]. Shandong Science, 2018, 31(1): 23-29. DOI: 10.3976/j.issn.1002-4026.2018.01.004 |
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| Authors: | YANG Long-fei DING Xiao-yan GAO Yan GUO Jin SUN Qi-hui ZHAO Bo-nian |
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| Affiliation: | 1.Shandong University of Traditional Chinese Medicine, Jinan 250355,China;2.Shandong Provincial key laboratory of Chinese Medicine Quality Standard Research,Shandong Academy of Chinese Medicine, Jinan 250014,China |
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| Abstract: | Based on the orthogonal design, parameters of the water extraction process of Tonglishu Granule were optimized by using gardenin content, peoniflorin content and the extract yield as the index. The experimental results showed that the optimal conditions for water extraction were as follows: eight times of water, extracting two hours and three times. The optimal extraction technology was reasonable and feasible, and the extraction efficiency was high, which could be used as the water extraction technology for Tonglishu Granule, and suitable for industrial producion. |
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| Keywords: | Tonglishu Granule water extraction process content determination extract yield orthogonal design |
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