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经皮层选择性海马杏仁核切除术治疗颞叶癫痫
引用本文:许尚臣,栾立明,庞琦,翟国德,葛明旭,孔大伟.经皮层选择性海马杏仁核切除术治疗颞叶癫痫[J].中华神经外科杂志,2006,22(12):732-734.
作者姓名:许尚臣  栾立明  庞琦  翟国德  葛明旭  孔大伟
作者单位:250021,济南,山东大学山东省立医院神经外科
基金项目:山东省自然科学基金资助项目(基金编号:05200140)
摘    要:目的 观察经皮层入路选择件海马含仁核切除术对颞叶癫痫的治疗效果及风险。方法 20例单侧海马硬化性顽崮性颞叶内侧癫痫患者,采用颢部开颅经颞中同侧脑室入路选择性海马杏仁核切除术治疗,随访至少1年以卜,采用Engel分级量表进行针对癫痫发作控制效果的评价。结果 Ⅰ级结果15例,Ⅱ级结果3例,Ⅲ级结果2例,无明显持久性并发症,无手术死亡。结论 在严格筛选的颞叶内侧癫痫,颞部开颅经颞中回皮层入路选择性切除海马含仁核术对治疗颞叶癫痫,安全有效。

关 键 词:颞叶癫痫  海马硬化  选择性海马杏仁核切除术
收稿时间:2006-08-23
修稿时间:2006-09-25

Treatment of temporal lobe epilepsy using transcortical selective mygdalohippocampectomy
XU Shang-chen, LUAN Li-ming, PANG Qi,et al..Treatment of temporal lobe epilepsy using transcortical selective mygdalohippocampectomy[J].Chinese Journal of Neurosurgery,2006,22(12):732-734.
Authors:XU Shang-chen  LUAN Li-ming  PANG Qi  
Affiliation:Department of Neurosurgery, Shandong Provincial Hospital, Shandong University, Jinan 250021, China
Abstract:Objective To observe the effectiveness and associated risks of trans-midtemporal trans- ventricle selective amygdalohippocampectomy via keyhole temporal craniotomy in treating mesial temporal lobe epilepsy.Methods 20 patients with intractable mesial temporal lobe epilepsy associated with unilateral hippocampal sclerosis were treated surgically using this surgical procedure and had been followed up more than 1 year.The outcome with respect to seizure control was evaluated according to Engel's outcome classification system.Results Class one outcome was obtained in 15 patients,class two outcome in 3 patients,class three outcome in 2 patients.No surgical mortality.No persistent neurological complications occurred.Conclusion In strictly selected patients with mesial temporal lobe epilepsy,this procedure is highly effective and safe.
Keywords:Mesial temporal lobe epilepsy  Hippocampal sclerosis  Selective amygdalohippocampectomy
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