腹股沟疝修补术后放置引流与否对血清肿形成的影响的Meta分析

目的分析比较腹股沟疝修补术后放置引流与不放置引流对预防血清肿形成的疗效。 方法检索PubMed、web of science、science direct、ovid和CNKI数据库，检索时限均为从建库至至2016年10月，选择腹股沟疝修补术后放置引流与不放置引流的临床对照研究，2位作者分别独立进行文献筛选、资料提取及质量评估，使用Cochrane 5.0.1系统评价手册进行Meta分析。 结果共纳入2项随机对照临床研究和4项回顾性临床对照研究，包括3 448例患者，其中术后放置引流组2 607例，术后未放置引流组841例。对纳入研究进行整体分析显示，放置引流组总体在减少术后血清中发生率方面高于未放置引流组（P=0.007），相对危险度为0.29，95%可信区间（CI）：0.12~0.72；放置引流组总体在增加手术时间方面高于未放置组（P=0.006），标准化均数差为0.36，95% CI：0.22~0.51。2组总体在住院时间比较，差异无统计学意义（P>0.05）。 结论腹股沟疝术后放置引流可以减少术后严重血清肿的形成，因此是安全可行的。

Meta-analysis of the effect of drainage after inguinal hernia repair on seroma formation

ObjectiveTo analyze the effect of drainage and non-drainage after inguinal hernia repair on the prevention of seroma formation. MethodsPubMed, web of science, science direct, ovid and CNKI databases were searched and submitted for search until October 2016. A controlled clinical study comparing drainage and non-drainage after inguinal herniorrhaphy was performed. The authors independently performed literature screenings. Data extraction and quality assessment were performed using the Cochrane 5.0.1 systematic review manual for meta-analysis. ResultsA total of 2 randomized controlled clinical studies and 4 retrospective clinical controlled studies were included, including 3 448 patients, of whom 2 607 were placed drainage after surgery and 841 without drainage. The overall analysis of the included studies showed that compared with the non-drainage group, the drainage group had a higher overall incidence in the reduction of postoperative seroma than the non-drainage group (P=0.007), relative risk was 0.29 (95% CI: 0.12-0.72); the overall increased operative time in drainage group was higher than that in non-drainage group (P=0.006), the STD Mean Difference was 0.36 (95% CI: 0.22-0.51). There was no significant difference in the length of hospital stay between the two groups. ConclusionDrainage after inguinal hernia surgery can reduce the formation of seroma, so it is safe and feasible.