糖尿病患者心自主神经系统功能与24 小时动态血压变化关系的探讨

目的 探讨偶测血压正常的糖尿病（ＤＭ）患者心自主神经系统功能（ＡＮＳＦ）状况与２４小时动态血压（２４小时ＡＭＢＰ）的变化关系。方法 对例偶测血压正常的ＤＭ患者进行心率功率谱分析及２４小时ＡＭＢＰ检测。结果 无压力负荷发生率明显高于正常对照组，而昼夜改变百分率明显低于正常对照组，伴工ＡＮ的ＤＭ患者，其２４小时动态收缩压及２４小时ＡＭＢＰ负荷发生率高一伴轻度ＡＮ的ＤＭ患者，昼夜改变百分率低于伴轻度ＡＮ

A study of relationship between function of cardiac autonomic nervous system and 24-hour ambulatory blood pressure in diabetes mellitus

Objective To study the relationship between function of cardiac autonomic nervous system and 24 hour ambulatory blood pressure in diabetes mellitus with normal blood pressure in the casual assay. Methods 71 DM patients with normal blood pressure in casual assay were measured with cardiac power spectral analysis and 24hAMBP assessment.Results There was no difference in 24hAMBP between DM patients without AND and normal subjects. 24 hour ambulatory systolic pressure values and the prevalence of blood pressure burden in DM patients with mild AND were significantly higher than that in the control group and the percentage of day night change in AMBP were significantly lower than that in the control group. In DM patients with severe AND, 24 hour ambulatory systolic pressure values and the prevalence of 24hAMBP burden were higher and the percentage of day night change was lower than that in DM patients with mild AND, however, there was no significant difference between them.Conclusion Blood pressure was in severe disorder as soon as cardiac AND appear in DM patients with normal casual blood pressure. Abnormality of ANSF and blood pressure in DM patients contributed to the onset and development of cardiovascular events. They are very important for investigating cardiac ANSF in DM patients and early intervening and treating DM patients with AND.