Older donors and kidney transplantation |
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| Authors: | T A Creagh P A McLean M G Donovan J J Walshe D M Murphy |
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| Affiliation: | (1) Department of Surgery, Beaumont Hospital, Dublin 9, Ireland;(2) Department of Urology, Beaumont Hospital, Dublin 9, Ireland;(3) Department of Transplantation, Beaumont Hospital, Dublin 9, Ireland;(4) The Royal College of Surgeons in Ireland, Dublin, Ireland |
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| Abstract: | Reluctance to use kidneys from older donors (>50 years of age) is based on reports of inferior results. We reviewed our experience with 45 kidneys transplanted from older donors. Primary nonfunction, immediate graft function, and 1-, 2- and 3-year graft survival rates were similar to those obtained with kidneys transplanted from donors aged between 20 and 40 years. Renal function at 1 year (as measured by serum creatinine) was poorer in kidneys from older donors. No beneficial effect with respect to graft survival was noted with cyclosporin therapy compared to conventional immunosuppression; however, the numbers are small. We conclude that kidneys from older donors are a valuable source for transplantation. |
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| Keywords: | Donor age kidney transplantation — Kidney transplantation older donors — Cyclosporin older donors kidney transplantation |
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