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甲基营养菌的研究进展
引用本文:晁红军,宋修鹏,孙继华,申佩弘,武波. 甲基营养菌的研究进展[J]. 微生物学通报, 2009, 36(11): 1727-1737
作者姓名:晁红军  宋修鹏  孙继华  申佩弘  武波
作者单位:广西亚热带生物资源保护利用重点实验室,广西,南宁,530005;微生物及植物遗传工程教育部重点实验室,广西,南宁,530005;广西大学生命科学与技术学院,广西,南宁,530005
基金项目:广西青年科学基金资助项目(No. 0832011); 广西科技攻关项目(No. 033002-5); 广西大学科研基金项目(No. X081074)
摘    要:甲基营养菌是一类能够利用一碳化合物作为唯一碳源和能源的微生物,它们在自然界分布广泛.研究表明,甲基营养菌能够直接利用一碳化合物,将其转化成自身代谢的一碳单位,并为生物体提供能源和碳骨架,这组成了一碳代谢的主要部分,它是一种新的代谢体系,可以作为一种新的代谢模式来研究生物代谢和生物进化.本文结合本实验室Methylobacterium sp.MB200的研究情况,主要从分类学、代谢途径、基因组学和应用等方面,论述了甲基营养菌的研究进展.

关 键 词:甲基营养  甲基杆菌  一碳化合物  一碳代谢

Advances in Methylotrophy
CHAO Hong-Jun,SONG Xiu-Peng,SUN Ji-Hu,SHEN Pei-Hong and WU Bo. Advances in Methylotrophy[J]. Microbiology China, 2009, 36(11): 1727-1737
Authors:CHAO Hong-Jun  SONG Xiu-Peng  SUN Ji-Hu  SHEN Pei-Hong  WU Bo
Affiliation:Key Laboratory of Subtropical Bioresource Conservation and Utilization of Guangxi, Nanning, Guangxi 530005, China; Key Laboratory of Microbial and Plant Genetics Engineering of the Ministry of Education, Nanning, Guangxi 530005, China; The College of Life;Key Laboratory of Subtropical Bioresource Conservation and Utilization of Guangxi, Nanning, Guangxi 530005, China; Key Laboratory of Microbial and Plant Genetics Engineering of the Ministry of Education, Nanning, Guangxi 530005, China; The College of Life;Key Laboratory of Subtropical Bioresource Conservation and Utilization of Guangxi, Nanning, Guangxi 530005, China; Key Laboratory of Microbial and Plant Genetics Engineering of the Ministry of Education, Nanning, Guangxi 530005, China; The College of Life;Key Laboratory of Subtropical Bioresource Conservation and Utilization of Guangxi, Nanning, Guangxi 530005, China; Key Laboratory of Microbial and Plant Genetics Engineering of the Ministry of Education, Nanning, Guangxi 530005, China; The College of Life;Key Laboratory of Subtropical Bioresource Conservation and Utilization of Guangxi, Nanning, Guangxi 530005, China; Key Laboratory of Microbial and Plant Genetics Engineering of the Ministry of Education, Nanning, Guangxi 530005, China; The College of Life
Abstract:Methylotrophy is a kind of widespread microbe which can use carbon compound as their only carbon and energy sources. It has been reported that methylotrophy can directly use one carbon compound to transform into their own metabolic one carbon unit, then these one metabolic one carbon units can be used as energy and carbon skeleton by organisms, which is a main part in one carbon metabolism. Because this is a novel metabolic system, it can be used in the study of biological metabolism and evolution. Based on the previous study about Methylobacterium sp. MB200 in our lab, here we summarized the research improvements about methylotrophy from their taxonomy, metabolism, genomics and applications.
Keywords:Methylotroph   Methylotrophic bacteria   One carbon compound   One carbon metabolism
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