| 苯磺酸左旋氨氯地平治疗高血压病合并阻塞性睡眠呼吸暂停综合征的疗效观察 |
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| 引用本文： | 兰莉,沈松林,张润峰,欧宁,陈斌,黄敏虎,唐波,王博雅.苯磺酸左旋氨氯地平治疗高血压病合并阻塞性睡眠呼吸暂停综合征的疗效观察[J].中国心血管病研究杂志,2017,15(7). |
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| 作者姓名： | 兰莉 沈松林 张润峰 欧宁 陈斌 黄敏虎 唐波 王博雅 |
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| 作者单位： | 绵阳市第三人民医院心血管内科,绵阳市第三人民医院心血管内科,绵阳市第三人民医院心血管内科,绵阳市第三人民医院心血管内科,绵阳市第三人民医院心血管内科,绵阳市第三人民医院心血管内科,绵阳市第三人民医院心血管内科,绵阳市第三人民医院 |
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| 基金项目： | 四川省医学会‘施慧达’科研课题（编号SHD14-14） |
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| 摘 要： | 【】目的 观察苯磺酸左旋氨氯地平与缬沙坦对高血压合并阻塞性睡眠呼吸暂停综合征患者的降压效果。方法 选取我院诊断轻、中度成人高血压合并阻塞性睡眠呼吸暂停综合征患者83例,通过服用安慰剂后2周,分为实验组43例、对照组40例,行24h动态血压监测后分别服用苯磺酸左旋氨氯地平、缬沙坦,坚持服药8周后行24h动态血压监测分析。结果 两组动态血压结果比较,实验组、对照组在分别使用降压药8周后,24h平均收缩压(24h SBP)与24h平均舒张压(24h DBP)、日间平均收缩压(dMSP)与平均舒张压(dMDP)、夜间平均收缩压(nMSP)与平均舒张压(nMDP),较用药前基础血压下降均有显著差异,P＜0.05。实验组与对照组两组间在24h SBP、24h DBP、dMSP、dMDP、nMDP比较无显著差异,P＞0.05。实验组与对照组两组间在dMSP比较有显著差异,P＜0.05。实验组与对照组疗效比较,实验组与对照组疗效比较无显著差异,P＞0.05。结论 苯磺酸左旋氨氯地平能够有效降低阻塞性睡眠呼吸暂停综合征合并高血压患者血压,与缬沙坦相比,无明显差异。
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| 关 键 词： | 高血压 阻塞性睡眠呼吸暂停低通气综合征 苯磺酸左旋氨氯地平 缬沙坦 |
| 收稿时间： | 2017/3/18 0:00:00 |
| 修稿时间： | 2017/6/4 0:00:00 |
Observe the antihypertensive effect of levamlodipine besylate on hypertension with obstructive sleep apnea syndrome |
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| SHEN Song-ling,ZHANG Run-feng,OU Lin,CHEN Bing,HUANG Min-hu,TANG Bo and WANG Bo-ya.Observe the antihypertensive effect of levamlodipine besylate on hypertension with obstructive sleep apnea syndrome[J].Chinese Journal of Cardiovascular Review,2017,15(7). |
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| Authors: | SHEN Song-ling ZHANG Run-feng OU Lin CHEN Bing HUANG Min-hu TANG Bo and WANG Bo-ya |
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| Affiliation: | Department of Cardiovascular Medicine,The first department of Psychosomatic disease,the third hospital of mianyangmianyang sichuan china,Department of Cardiovascular Medicine,The first department of Psychosomatic disease,the third hospital of mianyangmianyang sichuan china,Department of Cardiovascular Medicine,The first department of Psychosomatic disease,the third hospital of mianyangmianyang sichuan china,Department of Cardiovascular Medicine,The first department of Psychosomatic disease,the third hospital of mianyangmianyang sichuan china,Department of Cardiovascular Medicine,The first department of Psychosomatic disease,the third hospital of mianyangmianyang sichuan china,Department of Cardiovascular Medicine,The first department of Psychosomatic disease,the third hospital of mianyangmianyang sichuan china,Department of Cardiovascular Medicine,The first department of Psychosomatic disease,the third hospital of mianyangmianyang sichuan china |
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| Abstract: | |
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| Keywords: | Hypertension Obstructive sleep apnea hypopnea syndrome Levamlodipine besylate Valsartan |
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