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EARLY SURGERY TO PATIENTS SUFFERING FULMINANT ACUTE PANCREATITIS WITH ABDOMINAL COMPARTMENT SYNDROME
作者姓名:余枭  李永国  陈道瑾  李小荣  张圣道  雷若庆  汤耀卿
作者单位:[1]Department of Abdominal Surgery, the Third Xiangya Hospital, Central-South University, Changsha 410013, China [2]Department of Abdominal Surgery, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 20025, China
摘    要:Objective To retrospectively analyze and compare conservative versus surgical treatment of patients with fulminant acute pancreatitis ( FAP ) plus abdominal compartment syndrome ( ACS ). Methods From January 1998 to September 2005, 21 patients with FAP plus ACS were retrospectively analyzed. Ten patients were conservatively treated by means of intensive care medicine without surgery, and 11 patients received open surgical management and suction drainage. Results Seven of the 10 non-surgical patients died, comprising one with mild, four with moderate and two with severe ACS (70% mortality rate). Of the 11 patients receiving open surgical management in the early phase ( within 3 days of disease initiation ), three died, comprising one with moderate and two with severe ACS (27.3% mortality rate). The difference in mortality rates was found to be statistically significant. Conclusion Our data indicate patients suffering FAP with severe ACS should be treated with open management of the abdomen in the early phase ( within 3 days), even in the absence of infection. This approach appears superior to that of conservative management. Surgical treatment resulted in abdominal decompression and subsequently significantly decreased the mortality rate and improved overall prognosis.

关 键 词:手术治疗  急性胰腺炎  腹部疾病  临床表现
收稿时间:2005-12-05

EARLY SURGERY TO PATIENTS SUFFERING FULMINANT ACUTE PANCREATITIS WITH ABDOMINAL COMPARTMENT SYNDROME
YU Xiao,LI Yong-guo,CHEN Dao-jin,LI Xiao-rong,ZHANG Sheng-dao,LEI Ruo-qing,TANG Yao-qing.EARLY SURGERY TO PATIENTS SUFFERING FULMINANT ACUTE PANCREATITIS WITH ABDOMINAL COMPARTMENT SYNDROME[J].Journal of Shanghai Second Medical University(Foreign Language Edition),2006,18(2):94-98.
Authors:YU Xiao  LI Yong-guo  CHEN Dao-jin  LI Xiao-rong  ZHANG Sheng-dao  LEI Ruo-qing  TANG Yao-qing
Abstract:Objective To retrospectively analyze and compare conservative versus surgical treatment of patients with fulminant acute pancreatitis (FAP) plus abdominal compartment syndrome (ACS). Methods From January 1998 to September 2005, 21 patients with FAP plus ACS were retrospectively analyzed. Ten patients were conservatively treated by means of intensive care medicine without surgery, and 11 patients received open surgical management and suction drainage. Results Seven of the 10 non-surgical patients died, comprising one with mild, four with moderate and two with severe ACS (70% mortality rate). Of the 11 patients receiving open surgical management in the early phase (within 3 days of disease initiation), three died, comprising one with moderate and two with severe ACS (27.3% mortality rate). The difference in mortality rates was found to be statistically significant. Conclusion Our data indicate patients suffering FAP with severe ACS should be treated with open management of the abdomen in the early phase (within 3 days), even in the absence of infection. This approach appears superior to that of conservative management. Surgical treatment resulted in abdominal decompression and subsequently significantly decreased the mortality rate and improved overall prognosis.
Keywords:fulminant acute pancreatitis  abdominal compartment syndrome  surgery
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