| 2,4-二氯-5-甲氧基嘧啶的合成研究 |
| |
| 引用本文： | 刘永杰,姚新鼎,杨丽萍,雒廷亮,刘国际.2,4-二氯-5-甲氧基嘧啶的合成研究[J].现代化工,2009,29(Z1). |
| |
| 作者姓名： | 刘永杰 姚新鼎 杨丽萍 雒廷亮 刘国际 |
| |
| 作者单位： | 郑州大学化工与能源学院,河南,郑州,450001 |
| |
| 摘 要： | 2,4-二氯-5-甲氧基嘧啶是新型的嘧啶类中间结构体.以甲氧基乙酸甲醋、甲酸甲酯、尿素、三氯氧磷等为原料,经环合、氯化,合成了2,4-二氯-5-甲氧基嘧啶.反应条件优化后总收率可达到46%,产品纯度在99.5%以上.
|
| 关 键 词： | 5-甲氧基尿嘧啶 2 4-二氯-5-甲氧基嘧啶 合成 |
Research on synthesis of 2,4-dichloro-5-methoxy-pyrimidine |
| |
| LIU Yong-jie,YAO Xin-ding,YANG Li-ping,LUO Ting-liang,LIU Guo-ji.Research on synthesis of 2,4-dichloro-5-methoxy-pyrimidine[J].Modern Chemical Industry,2009,29(Z1). |
| |
| Authors: | LIU Yong-jie YAO Xin-ding YANG Li-ping LUO Ting-liang LIU Guo-ji |
| |
| Abstract: | 2,4-Dichloro-5-methoxy-pyrirnidine is a new intermediate compound of pyrimidine.In this paper methyl methoxyacetate,methyl formate,carbamide,phosphoryl chloride are used as raw materials to synthesize 2,4-dichloro-5-methoxypyrimidine,by cyclization and chloridization.And under optimal conditions the total yield of product Call be about 46%,with a purity higher than 99.5%. |
| |
| Keywords: | 5-methoxyuracil 2 4-dichIoro-5-methoxy-pyrimidine synthesis |
| 本文献已被 万方数据 等数据库收录！ |
|
