| 聚乳酸超细纤维膜的制备及降解性能研究 |
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| 引用本文： | 于建香,姚天宇. 聚乳酸超细纤维膜的制备及降解性能研究[J]. 北京石油化工学院学报, 2013, 21(4): 10-13 |
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| 作者姓名： | 于建香 姚天宇 |
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| 作者单位： | 北京石油化工学院材料科学与工程系,特种弹性体复合材料北京市重点实验室,北京102617;北京石油化工学院材料科学与工程系,特种弹性体复合材料北京市重点实验室,北京102617 |
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| 基金项目： | 北京市优秀人才培养资助项目（2012D005005000005）;2013年北京石油化工学院优秀青年教师和管理骨干培育计划项目 |
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| 摘 要： | 通过静电纺丝法制备了不同相对分子质量的聚乳酸和聚乳酸/羟基磷灰石(PLLA/HA)复合纤维膜。对纤维膜的微观结构、热性能及体外降解进行了分析。结果表明:实验中所制备的PLLA纤维膜具有珠串的微结构,经过体外降解后变成了多孔结构,该结构有利于细胞的吸附;PLLA/HA纤维复合膜中羟基磷灰石抑制了PLLA降解过程中的自催化作用,减缓了降解速率。
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| 关 键 词： | 聚乳酸 珠串形态 电纺丝 |
Preparation and in Vitro Degradation of PLLA Super Fiber Membrane |
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| YU Jian-xiang,YAO Tian-yu. Preparation and in Vitro Degradation of PLLA Super Fiber Membrane[J]. Journal of Beijing Institute of Petro-Chemical Technology, 2013, 21(4): 10-13 |
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| Authors: | YU Jian-xiang YAO Tian-yu |
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| Affiliation: | (Department of Materials Science and Engineering, Beijing Key Lab of Special Elastomer Composite Materials Beijing Institute of Petrochemical Technology, Beijing 102617, China) |
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| Abstract: | In this paper, non-woven micron-nanofiber mats of PLLA, PLLA/hydroxyapatite （HA） were successfully prepared via electrospinning technique. The mats were characterized by DSC, TG and SEM, and their degradation performance was studied too. The results indicate that PLLA fibers have bead-string morphology and the surface morphology changed to be porous after degradation. The alkaline HA nano-particles inhibited the self-catalysis of PLLA during the deg- radation . |
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| Keywords: | poly（1-1actic）（PLLA） bead-string morphology electrospinning |
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