| ~(10)Co-γ射线照射对小鼠脾细胞DNA、RNA及蛋白质合成的影响 |
| |
| 引用本文： | 孟紫强. ~(10)Co-γ射线照射对小鼠脾细胞DNA、RNA及蛋白质合成的影响[J]. 辐射防护, 1986, 0(3) |
| |
| 作者姓名： | 孟紫强 |
| |
| 作者单位： | 核工业部辐射防护研究所 |
| |
| 摘 要： | 本文报道了~(60)Coγ线照射对小鼠脾细胞 DNA、RNA 及蛋白质合成影响的实验研究。结果表明,小鼠脾细胞 DNA 合成在0.5戈瑞照射后即明显受到抑制,而 RNA、蛋白质的合成在2.5戈瑞照射后才受抑显著,表明 DNA 合成对电离辐射比 RNA、蛋白质合成更为敏感。γ线照射抑制这三种生物大分子合成的剂量-效应曲线均是多相形的。
|
| 关 键 词： | γ线照射 小鼠脾细胞 DNA RNA 蛋白质 |
EFFECTS OF ~(60)Co-GAMMA RAYS ON DNA,RNA AND PROTEIN SYNTHESES IN SPLEEN CELLS ISOLATED FRESHLY FROM C_(57)BL MICE |
| |
| Meng Ziqiang. EFFECTS OF ~(60)Co-GAMMA RAYS ON DNA,RNA AND PROTEIN SYNTHESES IN SPLEEN CELLS ISOLATED FRESHLY FROM C_(57)BL MICE[J]. Radiation Protection, 1986, 0(3) |
| |
| Authors: | Meng Ziqiang |
| |
| Abstract: | In this experiment,the effects of ~(60)Co-Gamma rays on DNA,RNA and protein syntheses in mouse spleen cells in culture were investigatedin vitro.~3H-TdR,~3H-UR and ~(14)C-leucine incorporations were used in theexperiment to reflect the abilities of DNA,RNA and protein syntheses resp-ectively.The findings showed that the syntheses of DNA,RNA and proteinin spleen cells were relatively sensitive to radiation.By statistical analysis,after spleen cells received a low dose of 0.5 Gy,a significant decrease in~3H-TdR incorporation was induced.and a dose of 2.5 Gy can induce signi-ficant decrease in ~3H-UR and ~(14)C-leucine incorporations.With the dosage(0 to 10 Gy),the dose-response curves of radiation-induced depression ofDNA,RNA and protein syntheses were polyphasic.DNA synthesis in spleencells was more sensitive to radiation than thief RNA and proteir synthesesin the dose range of 0 to 10 Gy. |
| |
| Keywords: | Gamma Radiation Mouse Spleen Cells DNA Synthesis RNA Synthesis Protein Synthesis |
| 本文献已被 CNKI 等数据库收录！ |
|
