| 头孢他啶单用与联用万古霉素治疗发热性中性粒细胞减少血液肿瘤患儿的疗效比较 |
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| 引用本文： | 杨光,唐锁勤. 头孢他啶单用与联用万古霉素治疗发热性中性粒细胞减少血液肿瘤患儿的疗效比较[J]. 中国药物应用与监测, 2006, 3(3): 44-46 |
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| 作者姓名： | 杨光 唐锁勤 |
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| 作者单位： | 解放军总医院小儿内科,北京,100853 |
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| 摘 要： | 目的:比较头孢他啶单用与联用万古霉素对治疗发热性中性粒细胞减少血液肿瘤患儿的疗效。方法:62例中性粒细胞减少伴发热的血液肿瘤患儿随机分为两组,A组32例联合应用头孢他啶和万古霉素,B组30例单独应用头孢他啶。结果:A组总有效率为84.4%,高于B组的60.0(P<0.05),A组退热时间亦较B组有降低的趋势,而两组不良反应发生率的差异无显著性(P>0.05)。结论:头孢他啶和万古霉素联合应用的抗菌谱广,疗效优于单用头孢他啶,可作为治疗血液肿瘤患儿中性粒细胞减少伴发热的经验性用药之一。
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| 关 键 词： | 头孢他啶 万古霉素 粒细胞减少症 儿童 |
| 文章编号： | 1672-8157(2006)03-0044-03 |
| 修稿时间： | 2006-02-01 |
A Study on Ceftazidime with or Without Vancomycin in the Treatment of Febrile Neutropenia in the Children with Cancers |
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| YANG Guang,TANG Suo-qin. A Study on Ceftazidime with or Without Vancomycin in the Treatment of Febrile Neutropenia in the Children with Cancers[J]. , 2006, 3(3): 44-46 |
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| Authors: | YANG Guang TANG Suo-qin |
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| Abstract: | Objective: To compare the effects of ceftazidime with or without vancomycin in the treatment of febrileneutropenia in the children with cancers.Methods: 62 patients were randomized divided into two groups.32 patients in groupA received ceftazidime with vancomycin, and 30 patients in group B received ceftazidime alone.Results: The total effectivityrate of group A was 84.4%, which was higher than that in group B with 60.0%( P>0.05) , and the antifebric time of group Awas shorter than that of group B.No significant difference was found in the incidence rate of side reaction between two groups.Conclusion: Ceftazidime and vancomycin combination is more effective than ceftazidime alone. |
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| Keywords: | Ceftazidime Vancomycin Neutropenia Child |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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