| 异帕米星联合头孢哌酮/舒巴坦治疗ICU泛耐药鲍曼不动杆菌肺部感染的临床疗效及安全性观察 |
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| 引用本文： | 李玮,肖雄箭,林建东.异帕米星联合头孢哌酮/舒巴坦治疗ICU泛耐药鲍曼不动杆菌肺部感染的临床疗效及安全性观察[J].医学研究杂志,2011,40(8):122-124. |
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| 作者姓名： | 李玮 肖雄箭 林建东 |
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| 作者单位： | 1. 福建省人民医院ICU,福州,350004
2. 福建医科大学附属第一医院ICU |
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| 摘 要： | 目的观察异帕米星联合头孢哌酮/舒巴坦治疗ICU泛耐药鲍曼不动杆菌肺部感染的临床疗效及安全性。方法 60例ICU泛耐药鲍曼不动杆菌肺部感染的重症患者随机分为异帕米星联合头孢哌酮/舒巴坦治疗组(A组)和对照组(B组,单纯应用头孢哌酮/舒巴坦),观察两组的临床疗效、细菌学疗效及肝肾功能指标的变化。结果异帕米星联合头孢哌酮/舒巴坦治疗组临床总有效率及细菌清除率明显高于对照组,部分临床生化指标好转,未出现肝肾功能指标恶化。结论异帕米星联合头孢哌酮/舒巴坦对ICU泛耐药鲍曼不动杆菌肺部感染具有良好的临床疗效,是一个值得推广的临床抗菌策略。
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| 关 键 词： | 异帕米星 鲍曼不动杆菌 临床疗效 |
| 收稿时间： | 2010/12/15 0:00:00 |
| 修稿时间： | 2010/12/21 0:00:00 |
The Clinical Efficacy and Safety of Isepamicin Combined with Cefoperazone/sulbactam in the Therapy of Pulmonary Infection of Extensively Drug-resistant Acinetobacter Baumannii in ICU |
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| Li Wei,Xiao Xiongiian,Lin Jiandong.The Clinical Efficacy and Safety of Isepamicin Combined with Cefoperazone/sulbactam in the Therapy of Pulmonary Infection of Extensively Drug-resistant Acinetobacter Baumannii in ICU[J].Journal of Medical Research,2011,40(8):122-124. |
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| Authors: | Li Wei Xiao Xiongiian Lin Jiandong |
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| Affiliation: | .Intensive Care Unit,The People′s Hospital of Fujian,Fujian 350004,China |
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| Abstract: | Objective To investigate the clinical efficacy and safety of Isepamicin combined with cefoperazone/sulbactam in the treatment of pulmonary infection of extensively drug-resistant Acinetobacter baumannii in ICU.Methods Sixty severe patients with pulmonary infection of extensively drug-resistant Acinetobacter baumannii in ICU were divided into the treatment group(group A,n=30) treated with Isepamicin combined with cefoperazone/sulbactam and the control group(group B,n=30) treated with cefoperazone/sulbactam.T... |
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| Keywords: | Isepamicin Acinetobacter baumannii Clinical efficacy |
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