羊水葡萄糖及白介素-6在胎膜早破中的意义

目的 探讨胎膜早破患者羊水中葡萄及白介素－6(IL－6）含量与宫内感染的关系。方法 随机选择1994－1999年70例无妊娠并发症的胎膜早破的患者，在B超引导下，经腹行羊膜腔内穿刺，抽取羊水，用葡萄糖氧化酶方法测定水中葡萄糖，用酶联免疫方法测定IL－6含量。结果 胎膜早破并宫内感染者，羊水葡萄糖含量明显下降，IL－6含量则明显增高，当羊水葡萄糖含量≤0．55mmol/L,IL-6含量≥315ng/L时，预测宫内感染的敏感性100％，特异性＞80．00％。结论 胎膜早破患者，测定羊水葡萄糖及IL－6含量，能早期快速预测宫内感染。

Determination of Amniotic Fluid Glucose and Interleukin 6in Premature Rupture of Membranes

Objective To study the relationship between amniotic cavity infection and the content of glucose and interleukin 6(IL 6) in amniotic fluid in premature rupture of membranes(PMOR) group. Methods To chose randomly 70 examples of PMOR patients without pregnant complication in 1994～1999. Leading by Brightness mode of ultrasound, amniotic fluid was obtained by puncturing the amnion through abdomen. Amniotic fluid glucose was determined quantitatively by "Glucose oxidizing enzyme", IL 6 was measured by enzyme linked immunosorbent assay. Results The content of glucose in amniotic fluid decreased obviously while the quantity of IL 6 increased distinctively in the group with PMOR and amniotic cavity infection. When the content of glucose in amniotic fluid was lower than 0.55 mmol/L while the quantity of IL 6 higher than 315 ng/L, the sensitivity of amniotic cavity infection was expected to be 100%, the specificity over 80%. Conclusion In the PMOR group, to determine the content of glucose and IL 6 in amniotic fluid can predict amniotic cavity infection rapidly and conveniently.