| 三氯生/SiO_2杂化材料的制备和抗菌性能 |
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| 引用本文： | 刘海弟,岳仁亮,张婧坤,吴镇江,陈运法.三氯生/SiO_2杂化材料的制备和抗菌性能[J].精细化工,2011,28(11):1046-1050. |
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| 作者姓名： | 刘海弟 岳仁亮 张婧坤 吴镇江 陈运法 |
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| 作者单位： | 中国科学院过程工程研究所多相复杂系统国家重点实验室,北京,100190 |
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| 基金项目： | 国家高技术研究发展计划(863)资助项目(2010AA064903)~~ |
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| 摘 要： | 以正硅酸乙酯、三氯生和γ-氨丙基三乙氧基硅烷(KH-550)为原料,制备了缓释型有机/无机复合抗菌材料。采用低温氮吸附、SEM、FTIR等手段表征了样品的比表面积、颗粒形貌和表面基团;通过摇床溶出实验检测了该复合材料的耐溶出性能;通过抑菌圈实验表征了样品的溶出抗菌性。研究发现,该方法所制备的有机/无机复合抗菌材料具有良好缓释性能,当添加KH-550时材料的耐溶出性提高。
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| 关 键 词： | 抗菌性能 二氧化硅 三氯生 有机/无机复合 功能材料 |
Preparation of Trichlosan/SiO_2 Composite Material and Investigation into Its Antibacterial Performance |
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| LIU Hai-di
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YUE Ren-liang
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ZHANG Jing-kun
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WU Zhen-jiang
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CHEN Yun-fa.Preparation of Trichlosan/SiO_2 Composite Material and Investigation into Its Antibacterial Performance[J].Fine Chemicals,2011,28(11):1046-1050. |
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| Authors: | LIU Hai-di YUE Ren-liang ZHANG Jing-kun WU Zhen-jiang CHEN Yun-fa |
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| Affiliation: | LIU Hai-di,YUE Ren-liang,ZHANG Jing-kun,WU Zhen-jiang,CHEN Yun-fa (State Key Laboratory of Multiphase Complex Systems,Institute of Process Engineering,Chinese Academy of Sciences,Beijing 100190,China) |
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| Abstract: | Sustained-release antibacterial organic/inorganic composite material was prepared with TEOS,trichlosan and γ-aminopropyl triethoxy silane(KH-550) as raw materials.Low-temperature N2 adsorption,SEM and FTIR methods were employed to investigate the BET specific surface area,particle morphology and functional group on the sample surface.Sustained-release ability of the as-made samples was investigated with dissolving experiment on rotary shaker.Bacteriostasis circle experiments were conducted to assess the dissolving antibacterial performance of the samples.It was revealed by the results that organic/inorganic composite antibacterial material with good sustained-release ability could be successfully prepared,and the sustained-release ability could be improved by coupling agent(KH-550). |
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| Keywords: | antibacterial performance silica trichlosan organic/inorganic composite functional materials |
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