| 儿童终末期肝病评分在胆道闭锁患儿肝移植中的应用 |
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| 引用本文： | 庞文博,陈亚军.儿童终末期肝病评分在胆道闭锁患儿肝移植中的应用[J].中华小儿外科杂志,2017(8):627-630. |
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| 作者姓名： | 庞文博 陈亚军 |
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| 作者单位： | 100045北京,国家儿童医学中心,首都医科大学附属北京儿童医院普外科 |
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| 摘 要： | 儿童终末期肝病(pediatric end-stage liver disease,PELD)评分系统是根据客观的实验室检查数据评估儿童肝脏疾病严重程度的模型,国际上用它来分配日益减少的供肝给儿童肝移植受者.对于Kasai手术效果不佳的胆道闭锁(biliary atresia,BA)患儿来说,肝移植成为唯一的选择.本文通过分析PELD评分系统与经典的临床肝功能Child分级、BA肝移植手术时机的选择、活体肝移植(living donor liver transplantation,LDLT)、肝纤维化、葛西手术(Kasai procedure,KP)以及肝移植手术预后之间可能存在的关联,旨在较全面的了解PELD评分在BA患儿肝移植中所发挥的作用,力求使其应用更加科学、合理.
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| 关 键 词： | PELD评分 胆道闭锁 肝移植 |
Application of pediatric end-stage liver disease score during liver transplantation for biliary atresia |
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| Pang Wenbo,Chen Yajun.Application of pediatric end-stage liver disease score during liver transplantation for biliary atresia[J].Chinese Journal of Pediatric Surgery,2017(8):627-630. |
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| Authors: | Pang Wenbo Chen Yajun |
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| Abstract: | Pediatric end-stage liver disease (PELD) scoring system is employed for evaluating the status of children with liver diseases to ensure that a donated liver is matched with a child in greatest need.For those with bilary atresia (BA),liver transplantation becomes necessary when Kasai procedure fails to achieve satisfactory bile flow.In this article,PELD score is compared with ChildTurcotte-Pugh score.And its application during liver transplantation for BA is also summarized to help ensure its optimal clinical outcomes. |
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| Keywords: | PELD score Biliary atresia Liver transplantation |
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