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Three new flavone C-glycosides from the aerial parts of Paraquilegia microphylla
Authors:Kai-Jie Xu  Xue-Min Xu  Wen-Long Deng  Lei Zhang  Ming-Kui Wang
Affiliation:1. Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences , Chengdu, 610041, China;2. Sichuan Key Laboratory of Quality and Innovation Research of Chinese Materia Medica, Sichuan Academy of Chinese Medicine Sciences , Chengdu, 610041, China
Abstract:Three new flavone C-glycosides, paraquinins A–C, were isolated from the aerial parts of Paraquilegia microphylla (Royle) Dromm. et Hutch, a Tibetan medicine distributed in the Qinghai-Tibet plateau. On the basis of 1D and 2D NMR evidence, their structures were elucidated as acacetin-6-C-β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranoside (1), acacetin-6-C- l-rhamnopyranosyl-(1 → 2)-β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranoside (2), and acacetin-6-C-α-l-rhamnopyranosyl-(1 → 2)-(6?-O-E-feruloyl)-β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranoside (3).
Keywords:Ranunculaceae  Paraquilegia microphylla  flavone C-glycoside  paraquinins A–C
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