Two novel furostanol saponins from Ophiopogon japonicus |
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| Authors: | Tao Zhang Peng Zou Li-Ping Kang He-Shui Yu Yi-Xun Liu Xin-Bo Song |
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| Affiliation: | 1. Beijing Institute of Radiation Medicine , Beijing, 100850, China;2. Beijing Institute of Radiation Medicine , Beijing, 100850, China;3. Tianjin University of Traditional Chinese Medicine , Tianjin, 300193, China;4. Tianjin University of Traditional Chinese Medicine , Tianjin, 300193, China |
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| Abstract: | Two novel furostanol saponins were isolated from the fresh tubers of Ophiopogon japonicus. Comprehensive spectroscopic analysis allowed the chemical structures of the compounds to be assigned as (25R)-26-[(O-β-d-glucopyranosyl-(1 → 2)-β-d-glucopyranosyl)]-22α-hydroxyfurost-5-ene-3-O-β-d-xylopyranosyl-(1 → 4)-O-[α-l-rhamnopyranosyl-(1 → 2)]-β-d-glucopyranoside (1, ophiopogonin F) and (25R)-26-[(O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranosyl)]-22α-hydroxyfurost-5-ene-3-O-β-d-xylopyranosyl-(1 → 4)-O-[α-l-rhamnopyranosyl-(1 → 2)]-β-d-glucopyranoside (2, ophiopogonin G). The rare furostanol saponins with two glucosyl residues at C-26 position were isolated from the natural source for the first time. |
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| Keywords: | Ophiopogon japonicus furostanol saponins ophiopogonin F ophiopogonin G |
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