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Carbazole alkaloids from the stems of Clausena excavata
Authors:Tawanun Sripisut
Affiliation:Natural Products Research Laboratory , School of Science, Mae Fah Luang University , Tasud, Muang, Chiang Rai, 57100, Thailand
Abstract:A new carbazole alkaloid, sansoakamine (8), together with 11 known compounds, was isolated from the stems of Clausena excavata. All structures were elucidated by spectroscopic methods. Compound 7 showed moderate anti-malarial activity against Plasmodium falciparum with a MIC value of 6.74 μg/ml.
Keywords:Clausena excavata  carbazole alkaloids  Rutaceae  sansoakamine
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