| 头孢曲松钠结晶工艺研究 |
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| 引用本文： | 李惠芬,乔俊华,蔡秋琴,张春波,刘华. 头孢曲松钠结晶工艺研究[J]. 河北化工, 2010, 33(12): 36-37 |
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| 作者姓名： | 李惠芬 乔俊华 蔡秋琴 张春波 刘华 |
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| 作者单位： | 华北制药奥奇德药业有限公司,河北石家庄052165 |
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| 摘 要： | 通过加晶种对头孢曲松钠的结晶工艺进行改进,收率在95%左右。产品粒度较好,晶体较大,流动性和质量稳定性得到改善。
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| 关 键 词： | 头孢曲松钠 结晶工艺 操作条件 |
Researches in Ceftriaxone Sodium Crystallization Process |
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| LI Hui-fen,QIAO Jun-hua,CAI Qiu-qin,ZHANG Chun-bo,LIU Hua. Researches in Ceftriaxone Sodium Crystallization Process[J]. Hebei Chemical Engineering and Industry, 2010, 33(12): 36-37 |
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| Authors: | LI Hui-fen QIAO Jun-hua CAI Qiu-qin ZHANG Chun-bo LIU Hua |
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| Affiliation: | (NCPC-Orchid Pharmaceuticals Co.,Ltd,Shijiazhuang 052165,China) |
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| Abstract: | Improving the ceftriaxone sodium crystallization process by seeding,the yield about 95% was reached.The crystal size is biger and crystal size distribution（CSD） is better than that without seeding,good flowablity,good quanlity and stability were also showed. |
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| Keywords: | ceftriaxone sodium crystallization process operation conditions |
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