营养素摄入不平衡与妊娠中毒症

本文追踪观察了42例正常孕妇,85例妊娠中毒症孕妇的膳食摄入情况及血清脂质、钙、锌、总蛋白、白蛋白等指标。发现:与正常孕妇相比,妊娠中毒症孕妇孕初期血清LDL-C/HDL-C、AI升高,HDL-C、HDL-C/TC、钙下降;孕末期血清TG、TC、LDL-C、LDL-C/HDL-C、AI、SFA、MUFA升高,HDL-C、HDL-C/TC、C_(18:2)、C_(18:3)、C_(20:4)、PUFA、P/S、钙、锌、总蛋白、白蛋白下降,并多数有显著性差异。经逐步回归分析,膳食中动物脂肪摄入量百分比与血清TC、LDL-C、LDL-C/HDL-C、AI水平回归关系密切;孕初期血清钙、孕末期血清P/S、A/G、LDL-C/HDL-C、AI与妊娠中毒症严重程度回归关系密切。本文还讨论了营养因素在妊娠中毒症发生与发展中的作用,并提出营养性防治建议。

IMBALANCE OF NUTRIENTS INTAKE AND TOXEMIA IN PREGNANCY

The nutritional status, serum lipids, protein, Ca, and Zn of 85 toxemic and 42 normal pregnant women were estimated longitudinally from the first trimester to delivery. The results of dietary survey revealed that correlative and regressive relationship closely existed between serum TC, LDL-C, LDL-C/HDL-C, AI, and percentage of animal fat. In the toxemic cases, there were significant increases of serum LDL-C/HDL-C, AI, and decrease of HDL-C, HDL-C/TC and Ca in the 1st trimester as compared with those of the normal. In the 3rd trimester, there were significant increases of serum TG, TC, LDL-C, LDL-C/HDL-C, AI and MUFA, and decrease of serum HDL-C, HDL-C/TC, Ca, Zn, total protein and albumin in the toxemic cases. The regressive relationship was found between GI (ges-tosis index) and serum Ca in the 1st trimester or GI and serum P/S, A/G, LDL-C/HDL-C, AI in 3rd trimester. The problem of nutritional factors on development of toxemic cases was discussed and some nutritional suggestions were made.