病灶切除与热灼联合术在难治性癫痫治疗中的应用

目的 研究病灶切除与热灼联合手术方法治疗继发性、难治性癫痫的临床效果。方法 对291例继发性、难治性癫痫患采取病灶切除与热灼联合手术的治疗方法，并随访观察此种联合手术方法对难治性癫痫的控制效果：结果 采用病灶切除与热灼联合手术后，291例患中，有211例(72．5％)发作消失，有50例(17．2％)发作减少50％以上，对癫痫总的有效控制率为89．7％，随访1．5～4．0年，平均23个月，211例发作消失的患中有83例(39．3％)已停服抗癫痫药；同时，病灶切除与热灼联合术无永久性的术后并发症：结论 病灶切除与热灼联合术治疗继发性、难治性癫痫，安全并且治疗效果令人满意。

Application of lesionectomy combined with bipolar coagulation on the treatment of intractable epilepsy

Objective To observe the clinical effects of lesionectomy combined with bipolar coagulation on the cortexes with epileptogenic foci in intractable epilepsy.Methods Two hundred and ninety-one cases of patients were managed by lesionectomy combined with bipolar coagulation and the rate of epilepsy-control after operation was studied.Results Among 291 cases of patients, seizures of 211 (72.5%) cases disappeared and paroxysm of 50 ( 17.2%) cases decreased by 50% and more. The general rate of epilepsy-control was 89.7%. The follow-up survey, which had lasted for 1.5 to 4.0 years, averaged 23 months, showed 83 (39.3%) cases in all patients whose seizures disappeared had already stopped taking anti-epilepsy drugs. Meanwhile, lesionectomy combined with bipolar coagulation had no post-operative complication.Conclusion Lesionectomy combined with bipolar coagulation is a safe management to treat intractable epilepsy and its clinical effect is satisfactory.