基于CiteSpace知识图谱及专利计量对黄精相关研究的可视化分析

目的 探究黄精的研究发展趋势，为黄精栽培、临床研究及产业发展提供参考，为迅速把握其研究内涵和聚焦研究热点提供一定借鉴。方法 从中国知网（CNKI）数据库和Web of Science核心合集数据库中检索黄精中、英文献，利用CiteSpace软件从发文量、发文作者、机构、国家和关键词等方面进行计量学分析；借助incopat数据库的自带分析软件和Excel从专利申请数量、地域、机构及发明人等方面对黄精专利进行分析。结果 近20年黄精的中、英文发文量均呈现阶段性的变化，特别是近5年呈快速增长态势。合作网络共现分析发现中、英文文献发文量最多的作者分别是李友元和鲍锦库；发文量最多的研究机构分别为贵州大学农学院和四川大学，其中中心性最高的机构是中国科学院，在机构合作中影响力较大；中国是英文文献发文量最多的国家，且与其他国家间存在较为广泛的联系，在黄精的相关研究领域中占有重要地位。中、英文文献关键词分析发现黄精成分分析从简单的理化性质研究转向化合物分子结构研究；栽培技术从简单的套种、间作等发展为更适宜的林下种植模式；药理作用研究则集中在调节糖脂代谢、防治糖尿病、抗氧化、抗衰老及抗抑郁等方面。目前黄精...

Visual analysis of related researches on Polygonati Rhizoma based on CiteSpace knowledge map and patent bibliometrics

Objective To explore the research development trend of Huangjing (Polygonati Rhizoma) and provide a reference for Polygonati Rhizoma cultivation, clinical research, industrial development and quickly understanding its connotations and identifying research hotspots. Methods The Chinese and English literatures of Polygonati Rhizoma were retrieved from CNKI database and Web of Science core collection database, and CiteSpace software was used to make a bibliometric analysis from the number of publications, authors, institutions, countries and keywords; The patents of Polygonati Rhizoma were analyzed from the aspects of the number of applications, geographic regions, organizations and inventors with the help of incopat database’s own analysis software and Excel. Results Over the past two decades, the trend in publication outputs for both English and Chinese articles on Polygonati Rhizoma had exhibited phased fluctuations. Notably, there had been a marked surge in publication numbers in the last five years. The co-occurrence analysis of collaboration networks showed that the authors of the largest number of publications in Chinese and English literature were Li Youyuan and Bao Jinku, respectively. The College of Agriculture of Guizhou University and Sichuan University were the research institutions with the most publications in Chinese and English, respectively. Furthermore, the Chinese Academy of Sciences holded the highest degree of centrality, which had significant influence in the institutional collaboration network; China was the country with the largest number of English-language publications, and had more extensive connections with other countries, making a significant player in the field of Polygonati Rhizoma research. The analysis of keywords in Chinese and English literature showed that the analysis of constituents of Polygonati Rhizoma had shifted from simple research on physicochemical properties to understanding the molecular structures of compounds; The cultivation technology had developed from basic method of seed sowing, intercropping, etc. to more suitable undergrowth planting pattern; The research on pharmacological effects focuses on the regulation of glucose and lipid metabolism, prevention and treatment of diabetes mellitus, anti-oxidant, antiageing, and antidepressant. At present, the number of patent applications of Polygonati Rhizoma was in a downward trend, and there were more patent applications in China and other Asian countries where the influence of traditional Chinese medicine culture is greater, and the content of patent protection focuses on the compatibility of Polygonati Rhizoma. Conclusion The research of Polygonati Rhizoma is still in the stage of development and has attracted extensive attention from scholars at home and abroad. Currently, the prevention and treatment of diabetes, anti-oxidant, anti-aging, and antitumor are the research focus of Polygonati Rhizoma, and will remain the main research direction in the future. Among them, the regulatory effects of active components of Polygonati Rhizoma on intestinal flora structure and immunity, as well as its target and signaling pathway, will be the focus of research. The in-depth development and innovation of Polygonati Rhizoma products will also be a development area that needs high attention.