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COMBINATION THERAPY OF DRUG-RESISTANT CHORIOCARCINOMA
作者姓名:蔡树模  范建玄  李子庭  陈历排
作者单位:Cancer Hospital,Shanghai Medical University,Shanghai,200032
摘    要:COMBINATIONTHERAPYOFDRUG-RESISTANTCHORIOCARCINOMA¥CaiShumo;FanJianxuan;LiZiting;ChenLipai蔡树模,范建玄,李子庭,陈历排(CancerHospital,Shang...


Combination therapy of drug-resistant choriocarcinoma
Shumo Cai,Jianxuan Fan,Ziting Li,Lipai Chen.COMBINATION THERAPY OF DRUG-RESISTANT CHORIOCARCINOMA[J].Chinese Journal of Cancer Research,1994,6(4):284-288.
Authors:Shumo Cai  Jianxuan Fan  Ziting Li  Lipai Chen
Affiliation:1. Cancer Hospital, Shanghai Medical University, 200032, Shanghai, China
Abstract:From Jan. 1983 to June 1990, 35 drug-resistant choriocarcinoma treated in other hospitals were referred to our hospital. Among them, 88.6% of patients had already undergone more than 5 courses of chemotherapy, and the tumour showed resistance to at least 3 anti-choriocarcinoma drugs. PBA or PVBA regimen of chemotherapy as the main treatment was combined with irradiation or surgery. The 1, 2, and 3-year survival rates of PBA group were 60%, while 1 and 2-year survival rates of PVBA group were 73.3% and 75% respectively.The more the varieties of resistant drugs and the more the courses of previous chemotherapy had undergone,the worse the prognosis would be. The authors believe that the PVBA chemotherapy is very effective for drugresistant choriocarcinoma.
Keywords:Combination therapy  Drug-resistantchoriocarcinoma  
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