| 肺结核患者血清白介素18的定量检测 |
| |
| 引用本文： | 陈心春,李美忠,王火生,蔡雄茂,周伯平.肺结核患者血清白介素18的定量检测[J].临床肺科杂志,2001,6(2):3-4. |
| |
| 作者姓名： | 陈心春 李美忠 王火生 蔡雄茂 周伯平 |
| |
| 作者单位： | 深圳市东湖医院,518020 |
| |
| 摘 要： | 目的 探讨白介素18（Interleulin-18,IL-18）在抗结核菌感染中的作用。方法 采用酶免疫技术（ELISA）检测40例肺结核患和20例健康人群血清中IL－18和r干扰素（Interferon-r,IFN-r）。结果 肺结核患血清中IL－18和IFN－r水平均显地健康对照。IL－18水平和IFN－r水平呈明显的相关性。结论 IL－18可能在肺结核菌感染免疫中发挥重要作用。
|
| 关 键 词： | 白介素18 r干扰素 肺结核 定量检测 |
Measurement of interleukin-18 in serum of patients with pulmonary tuberculosis |
| |
| CHEN Xinchun,LI Meizhong,WANG Huosheng,et al..Measurement of interleukin-18 in serum of patients with pulmonary tuberculosis[J].Journal of Clinical Pulmonary Medicine,2001,6(2):3-4. |
| |
| Authors: | CHEN Xinchun LI Meizhong WANG Huosheng |
| |
| Affiliation: | CHEN Xinchun,LI Meizhong,WANG Huosheng,et al.Shenzhen Eastlake Hospital,518020,Shenzhen |
| |
| Abstract: | Objective To investigate the role of interleukin 18(IL 18) in human tuberculosis.Method The serum levels of IL 18 and interferon r(IFN r)in 40 patients with pulmonary tuberculosis and 20 healthy controls were evaluated by ELISA.Results The levels of IL 18 and IFN r in pulmonary tuberculosis were significantly higher than those of healthy control subjects.Circulating IL 18 significantly correlated with circulating IFN r.Conclusion IL 18 may play an important role in immune response to human infection with Mycobacterium tuberculosis. |
| |
| Keywords: | Interleuking 18 Interferon r Pulmonary tuberculosis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
