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甲氨喋呤联合米非司酮治疗异位妊娠的疗效观察
引用本文:柯宇桦.甲氨喋呤联合米非司酮治疗异位妊娠的疗效观察[J].海南医学院学报,2009,15(9):1133-1134,1138.
作者姓名:柯宇桦
作者单位:广东省吴川市人民医院妇产科,广东,吴川,524500
基金项目:海南医学院科研基金资助学报项目 
摘    要:目的:观察甲氨喋呤(Mrrx)联合米非司酮与单用米非司酮治疗异位妊娠的疗效。方法:A组MTX单次肌内注射并口服米非司酮;B组:米非司酮口服。定期测血B-HCG直至正常。结果:治愈率A组为94.74%,B组为81.25%,A组较B组明显缩短血p—HCG降至正常所需时间,减少住院日(P〈0.01)。结论:MTX单次肌内注射联合米非司酮治疗输卵管妊娠疗效好,不良反应少,值得临床推广。

关 键 词:妊娠  异位  甲氨喋呤  米非司酮

Therapeutic observation of Methotrexate-Mifepristone in patient with ectopic gestation
KE Yu-hua.Therapeutic observation of Methotrexate-Mifepristone in patient with ectopic gestation[J].Journal of Hainan Medical College,2009,15(9):1133-1134,1138.
Authors:KE Yu-hua
Affiliation:KE Yu-hua (Department of Gynaecology and Obstetrics, Wuchuan People's Hospital Wuchuan 524500, China)
Abstract:Objective:To observe the therapeutic effects of Methotrexate(MTX)-mifepristone on patients with ectopic gestation.Methods:MTX was injected intramuscularly once with oral administration of Mifepristone in group A.In group B,which were treated with oral administration of Mifepristone,serum β-HCG was regularly tested till normal.Results:The cure rate was 94.74% in group A,and 81.25% in group B,the time of β-HCG decreased to normal and hospitalization were shorter in group A than that in group B(P﹤0.01).Conclusions:MTX injected intramuscularly once with oral administration of Mifepristone has prefer able therapeutic effects and less adverse effects in patients with oviductal pregnancy.
Keywords:Ectopic gestation  Methotrexate  Mifepristone
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