三种不同手术方式联合丝裂霉素C治疗翼状胬肉的疗效比较

目的评价三种不同术式联合丝裂霉素C（MMC）治疗翼状胬肉的疗效。方法将90例120眼翼状胬肉患者，随机分为A、B、C三组。A组30例（35眼），B组30例（40眼），C组30例（45眼）。h组行常规翼状胬肉切除巩膜暴露疗法；B组行翼状胬肉切除羊膜移植；C组行翼状胬肉切除自体角膜缘干细胞移植，三种方式均术中联合丝裂霉素C。术后随访观察12～24个月，观察胬肉复发情况。结果a组：胬肉复发10例。B组：胬肉复发3例。C组：胬肉复发2例。A组与B、C两组比较差异有统计学意义（P〈0．05），B、C两组比较差异无统计学意义。结论翼状胬肉切除联合自体角膜缘干细胞移植及羊膜移植术治疗初发性翼状胬肉术后复发率均较低，其中自体角膜缘干细胞移植术更是治疗翼状胬肉的理想术式。

Clinical analysis of 186 aged patients with upper gastrointestinal hemorrhage in the

Objective To investigate the clinical features of upper gastrointestinal hemorrhage in aged patient. Methods The clinical features of 186 aged patients with upper gastrointestinal hemorrhage treated in our hospital from January 2006 to December 2007 were retrospectively analyzed and compared with that of 430 young cases during the same time. Results The main cause of upper gastrointestinal hemorrhage in aged patients was also peptic ulcer (53.7%), and the bleeding rate of gastric ulcer (32.79%) was more than that of duodenal ulcer (20.97%), unlike the young cases have a higher bleeding rate of duodenal ulcer. The second cause of upper gastrointestinal hemorrhage in aged patients was gastric cancer. Conclusion The main canse of upper gastrointestinal hemorrhage in aged patients was peptic ulcer. The bleeding rate of gastric ulcer and gastric cancer increased significantly, and with a higher rate of complication, rehaemorrhagia and mortality.