OCTA检测高度近视患者视网膜脉络膜厚度及血流变化的研究进展

高度近视是指近视度数在-6.00D以上的一种屈光不正状态。由于高度近视常常伴随多种眼底病理性改变，因此高度近视患者的视功能受到不同程度损害。光学相干断层扫描血管成像(OCTA)作为一种新兴的眼科辅助检查手段，可以高效、无创地得到视网膜、脉络膜的微血管分层图像，并对血流信号进行量化分析。自OCTA问世以来，运用OCTA观察高度近视眼底改变的研究层出不穷。本文通过对OCTA检测高度近视患者视网膜脉络膜厚度及血流变化的研究现状进行综述，以期揭示高度近视与视网膜脉络膜厚度、血流密度以及中心凹无血管区面积等参数的相关性，为科研人员深入探索高度近视发生机制，延缓高度近视发生发展提供思路。

Research progress of optical coherence tomography angiography in detecting retinal and choroidal thickness and blood flow in patients with high myopia

High myopia is a state of refractive error with myopia over -6.00D. High myopia is typically accompanied by multiple fundus lesions, thus making patients with high myopia suffer from varying degrees of impairment in visual function. As an emerging auxiliary way in ophthalmology, optical coherence tomography angiography(OCTA)can efficiently and non-invasively obtain microvascular stratified images of the retina and choroid and quantitatively analyze blood flow signals. Since the advent of OCTA, there have been numerous studies observing fundus changes in those with high myopia through OCTA. In this paper, some studies in which OCTA is applied to obtain retinal and choroidal thickness from patients with high myopia are reviewed, with a view to revealing the correlation between high myopia and the parameters such as retinal thickness, choroidal thickness, vessel density and the area of the foveal avascular zone and providing novel ideas to deeply investigate the mechanism of high myopia and delay the occurrence and development of high myopia.