保护性临时起搏对急性下壁心肌梗死急诊介入治疗再灌注低血压恢复时间及药物使用的影响

目的：探讨保护性临时起搏对急性下壁心梗（AIMI）患者急诊经皮冠状动脉介入治疗（PCI）再灌注低血压恢复时间和药物使用情况的影响。方法：在符合入选标准的AIMI，且成功完成急诊PCI的住院患者中，选择保护性起搏和非保护性起搏患者各52例，以收缩压〈90mmHg和／或舒张压〈60mmHg为低血压标准，两组分别有保护性起搏再灌注低血压组（23例），非起搏再灌注低血压组（16例）。观察两组再灌注低血压患者的药物使用情况以及低血压的缓解时间。结果：保护性起搏与非起搏再灌注低血压两组患者需要使用药物治疗比例无明显差别（78．3％比81．3％，P=0．820）。两组用药后低血压恢复时间亦无明显差别（〈5min恢复依次分别为92．3％，88．9％，P〉0．05）。结论：保护性临时起搏无减少再灌注低血压恢复时间及药物使用的作用。

Influence of protective temporary pacing on relieve duration of reperfusion hypotension and drug use in AIMI patients undergoing emergency PCI

Objective:To study influence of protective temporary pacing(PTP) on relieve duration of reperfusion hypotension(RH) and drug use in patients with acute inferior myocardial infarction(AIMI) undergoing emergency percutaneous coronary intervention(PCI).Methods:Among AIMI inpatients undergoing successive emergency PCI,52 PTP patients(PTP group) and 52 non-PTP patients(no-PTP group) were selected.According to RH standard(systolic blood pressure <90mmHg and/or diastolic blood pressure <60mmHg),23 cases from PTP group composed PTP-RH group and 16 cases from non-PTP group composed no-PTP-RH group.Drug use and relieve duration of hypotension were observed in two RH groups.Results:There were no significant difference in percentage of patients who needed drug treatment(78.3% vs.81.3%,P=0.820) between two RH groups.Ratio of patients with blood pressure recovered within five minutes after drug use in PTP group and no-PTP group was 92.3%,88.9% respectively(P>0.05).Conclusion:Protective temporary pacing has no obvious effect in reducing relieve duration of reperfusion hypotension and drug use.