| 生物制剂在炎症性肠病治疗中的现状和前景 |
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| 引用本文： | 吴汗,杨太明. 生物制剂在炎症性肠病治疗中的现状和前景[J]. 昆明医学院学报, 2012, 0(Z1): 31-34 |
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| 作者姓名： | 吴汗 杨太明 |
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| 作者单位： | 昆明医学院第一附属医院消化内科;云南省临沧市人民医院消化内科 |
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| 摘 要： | 炎症性肠病(IBD)是一种发生在肠道的病因不明的慢性非特异性炎性病变,包括溃疡性结肠炎(UC)和克罗恩病(CD),其发病原因尚不清楚,发病机制尚未完全阐明.目前,随着免疫学和生物学的发展,越来越多的生物学制剂用于IBD的治疗,使炎症性肠病的治疗在传统治疗的基础上,增加了对疾病本身的并发症或治疗有关的并发症的预防,从而改善了患者的生活质量,减少了住院率和外科手术率.这也是生物药物治疗的发展方向.就IBD的生物药物治疗现状和前景作一简要综述.
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| 关 键 词： | 炎症性肠病 生物治疗 临床应用 |
Current Status and Prospects of Biological Agent Therapy for Inflammatory Bowel Disease |
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| WU Han,YANG Tai-ming. Current Status and Prospects of Biological Agent Therapy for Inflammatory Bowel Disease[J]. Journal of Kunming Medical College, 2012, 0(Z1): 31-34 |
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| Authors: | WU Han YANG Tai-ming |
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| Affiliation: | 1)Dept.of Gastroenterology,The Affiliated Hospital of Kunming Medical University,Yunnan Kunming 650031;2)Dept.of Gastroenterology,The People’s Hospital of Lincang,Lincang Yunnan 677000,China) |
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| Abstract: | Inflammatory bowel disease(IBD),is a chronic non-specific inflammatory disorder with unknown etiology,including ulcerative colitis and Crohn’s disease(CD).With the development of immunological and biological studies,more and more biological agents have been studied and used for the treatment of IBD,Consequently,the clinical outcome of IBD is unsatisfying.A variety of new biological therapies have being developed in recent years.These therapies are shown to be helpful in inducing remssion,preventing complication,inproving life quality of the patients,and reducing hospitalization rates and surgical rates.which is a direction for future development of agent therapy.This review summarized the curret status and prospects of biological agent therapy for IBD. |
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| Keywords: | Inflammatory bowel disease Biological therapy Clinical application |
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