磁共振压缩感知心脏电影成像相较于常规心脏电影成像在急性心肌梗死术后心功能评价的对比研究

目的探讨磁共振压缩感知心脏电影成像相较于常规心脏电影成像在急性心肌梗死术后心功能评价中的优势和价值。材料与方法对30例ST段抬高型心肌梗死(ST-segment myocardial infarction,STEMI)的经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后患者,使用中国联影uMR 7803.0 T磁共振,扫描压缩感知心脏电影序列(以下简称uCS-Cine),与常规心脏电影序列(以下简称standard-Cine),扫描8层心脏短轴位电影(slice1-slice8)覆盖心尖至心底,其中uCS-Cine由一次屏气完成全心扫描,扫描参数:层厚8 mm,层间隔4 mm,TR 2.73 ms,TE 1.36 ms,TA=12.7 s,standard-Cine分8次屏气完成全心扫描,扫描参数:层厚8 mm,层间隔4 mm,TR 2.82 ms,TE 1.30 ms,TA=150 s。由2名影像科诊断医师就2种序列的各8层图像的心肌信噪比(signal to noise ratio,SNR)进行测量并比较,并对解剖结构显示情况,伪影情况,以及能否满足诊断需要以5分制评分量表分别进行主观评分,应用uWS-780工作站对两序列进行心功能分析。所得结果由SPSS 21.0软件通过配对秩和检验进行评价。结果30例患者的心功能分析结果显示,uCS-Cine和standard-Cine序列在左心室射血分数(left ventricular ejection fraction,LVEF)与左心室收缩末期容积(left ventricular end systolic volume,LVESV)结果没有统计学意义(P>0.05),左心室舒张末期容积(left ventricular end diastolic volume,LVEDV)结果standard-Cine稍大于uCS-Cine,结果具有统计学意义(P<0.05)。在图像质量客观评分方面,standard-Cine在slice1-slice8层面的心肌SNR均高于uCS-Cine,结果具有统计学意义(P<0.05)。在图像质量主观评分方面,uCS-Cine序列相较于standard-Cine,在slice1-slice6层面,图像质量评分没有统计学意义(P>0.05),在slice7-slice8层面,传统standard-Cine的图像质量主观评分优于uCS-Cine,结果具有统计学意义(P<0.05)。结论基于压缩感知技术的uCS-Cine相较于常规standard-Cine在心功能分析以及图像质量主观评分方面无明显差异,且可以极大的缩短检查时间,提高检查成功率,具有较高的临床应用价值。

A comparative study on the evaluation of cardiac function in patients with acute myocardial infarction using compressed sensing cardiac cine imaging compared with traditional cardiac cine imaging

Objective:To investigate the advantage and value of compressed sensing cardiac cine imaging compared with traditional cardiac cine imaging in evaluation of cardiac function after acute myocardial infarction.Materials and Methods:Thirty patients with ST-segment myocardial infarction(STEMI)myocardial infarction after percutaneous coronary intervention(PCI)were scanned with United imaging UMR 7803.0 T MRI,the uCS-Cine sequence based on compressed sensing technology,and the traditional sequence based on balanced steady-state free precession cardiac cine sequence(standard-Cine).The 8-slice images covered the apex to the bottom of the heart.The u CS-Cine whole heart scan was completed by one breath holding.Scanning parameters:slice thickness 8 mm,interval 4 mm,TR/TE=2.73/1.36 ms,TA=12.7 s.The standard-Cine was performed with 8 breath holding.Scanning parameters:slice thickness 8 mm,interval 4 mm,TR/TE=2.82/1.30 ms,TA=150 s.Two experienced radiologists evaluated the signal to noise ratio(SNR)of cardiac muscle,and the display of anatomical structures,artifacts and whether they could meet the needs of diagnosis on 8 layers(apex as the first layer and bottom as the eighth layer).The cardiac function of the two sequences was analyzed by uWS-780 workstation.The results were evaluated by SPSS 21.0 software by paired rank sum test.Results:The results of cardiac function analysis of 30 patients showed that there was no significant difference in left ventricular ejection fraction(LVEF)and left ventricular end systolic volume(LVESV)between uCS-Cine and standard-Cine sequences(P>0.05),while the standard-Cine of left ventricular end diastolic volume(LVEDV)was slightly larger than that of uCS-Cine(P<0.05).In terms of the objective score of image quality,the SNR of cardiac muscle of standard-Cine in slice1-slice 8 was higher than that in uCS-Cine(P<0.05),and in terms of subjective image quality score,compared with standard-Cine sequence,8-layer short axis images covered from apex to bottom of heart.At slice1-slice6 level,image quality score was not statistically significant(P>0.05),while in slice7-slice8 level,the subjective score of traditional standard-Cine was better than that of uCS-Cine,and the results were statistically significant(P<0.05).Conclusions:Compared with the conventional standard-Cine,the uCS-Cine based on compressed sensing technology has no significant difference in heart function analysis and subjective score of image quality,and can greatly shorten the examination time,improve the success rate of examination,and has high clinical application value.