氨氯地平联合卡托普利治疗冠心病并高血压疗效观察

目的探讨氨氯地平联合卡托普利治疗高血压合并冠心病患者的疗效。方法80例高血压合并冠心病患者随机分为治疗组和对照组，每组40例，治疗组应用氨氯地平和卡托普利，对照组采用氢氯噻嗪、尼群地平、硝酸异山梨酯等药物治疗。治疗8周后观察两组患者血压、心绞痛缓解情况及心电图改变情况。结果治疗组收缩压和舒张压明显低于对照组（P〈0．05）；治疗组冠心病治疗总有效率、心电图改善率分别为：90．0％、72．5％，明显高于对照组的67．5％、52．5％（均P〈0．05）。结论氨氯地平联合卡托普利治疗高血压合并冠心病疗效满意，能有效缓解冠心病患者心绞痛发作。

Therapeutic effect of combined medication of amlodipine and captopril on patients with hypertension complicated with coronary heart disease

Objectlve To study the therapeutic efficacy of the combined medication of ShiHuiDa and capto pril on patients with by Opertension and coronary heart disease.Methods 80 patients witll hypertension complicated with coronary disease were included in this study.They were randomly dirided in to treatment group and control group,every group is forty patients.Treatment group treated by ShiHuiDa and captopril,control group treated by hydrocblorothiazide nitrendipine and dinitrosorbide.Blood pressure angina pectoris relief and electrocardlogram were observed after eight weeks therapy.Results Systolic pressure and diastolic pressure in treatment group is less than control group,it is obviously better than control group about depressurization effect,it has significant difference by statistical test.Angina pectoris relief rate and electrocardiogram improve rate in treatment group is better than control group,it has significant difference.Conclusion The combined medication of ShiHuiDa and captopril is not only effective in lowering blood pressure and stronger and persistence,but also in relieving angna pectoris attack.