邢台地区部分围绝经期女性甲状腺结节现状及影响因素分析*

目的 了解邢台地区部分围绝经期女性甲状腺结节的发生状况，并分析其影响因素。方法 选取2019年全年在邢台市人民医院健康体检中心进行体检的1 038例围绝经期女性作为研究对象，对其基本情况和部分检查结果进行统计学分析。结果 本文中1 038例围绝经期女性甲状腺结节的检出率高达57.4%。围绝经期女性甲状腺结节的发生与年龄、体质指数（BMI）、是否绝经和是否患脂肪肝有关，差异均有统计学意义（P<0.05）。甲状腺结节的检出率随年龄的增加而逐步升高，年龄分级在55~60岁组别甲状腺结节的检出率最高；绝经人群甲状腺结节检出率高于未绝经人群；脂肪肝人群甲状腺结节检出率高于非脂肪肝人群。甲状腺结节组总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、空腹血糖（FPG）均高于非甲状腺结节组，差异有统计学意义（P<0.05）。多因素 Logistic 回归分析结果显示，绝经、年龄增高是围绝经期女性甲状腺结节患病的关键因素。结论 邢台地区围绝经期女性甲状腺结节患病率在全国范围内处于较高水平。围绝经期是甲状腺结节患病的高危因素，建议该人群定期进行体检，同时加强围绝经期女性甲状腺结节的筛查力度与管理力度。

Analysis of Status and Influencing Factors of Thyroid Nodule in some Perimenopausal Women in Xingtai Area

Objective To understand status and related influencing factors of Thyroid nodule in some perimenopausal women in Xingtai area. Methods Selecting in February 2019 to December in Center of Xingtai people''s Hospital Xintai city, 1 038 perimenopausal women cases as the research object, the self-compiled basic information questionnaire and physical examination results were used for statistical analysis. Results The prevalence of Thyroid Nodule was 57.4 %.There are significant difference of Thyroid Nodule in perimenopausal women among age, body mass index (BMI), menopause and fatty liver(P<0. 05).The prevalence of Thyroid Nodule showed a significant upward trend with the increase in age.The highest prevalence was observed between 55 and 60 years old.The prevalence of Thyroid Nodule in menopausal population was higher than that in non-menopausal population.The prevalence of Thyroid Nodule in fatty liver group was higher than that in non-fatty liver group.There are significant difference in Total cholesterol(TC), low density lipoprotein cholesterol (LDL-C), fasting blood glucose(FPG) influenced by thyroid nodule group was higher than with-out thyroid nodule group(P<0. 05) . Multivariate logistic regression analysis identified menopause and advanced age as the influencing factors for Thyroid Nodule in perimenopausal women. Conclusion The prevalence of Thyroid Nodule in perimenopausal women in Xingtai area is high. perimenopausal period is a high risk factor for Thyroid Nodule,suggesting regular physical examination,the screening and management should be further strengthened in perimenopausal women with thyroid nodules.